Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272118 | 0.89 | KEAP1 (0.35) | KEAP1NFE2L2L3MBTL1MMP9MMP13 | |
| SCHEMBL271937 | 0.88 | POLB (0.37) | KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL271470 | 0.86 | NFE2L2 (0.33) | KEAP1NFE2L2L3MBTL1HDAC6MMP1 | |
| SCHEMBL271924 | 0.85 | POLB (0.32) | KEAP1NFE2L2 | |
| SCHEMBL271422 | 0.83 | TSHR (0.32) | KEAP1NFE2L2 | |
| SCHEMBL271791 | 0.83 | P2RX7 (0.35) | KEAP1NFE2L2MMP1MMP9MMP13 | |
| SCHEMBL271591 | 0.82 | RORC (0.37) | KEAP1NFE2L2 | |
| SCHEMBL271720 | 0.81 | SCD (0.35) | KEAP1NFE2L2HDAC6 | |
| SCHEMBL272027 | 0.81 | KEAP1 (0.35) | KEAP1NFE2L2L3MBTL1 | |
| SCHEMBL271319 | 0.81 | POLB (0.35) | KEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | KEAP1 34/4885NFE2L2 715/4885L3MBTL1 2902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.