Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009591 | 0.78 | MAOA (0.43) | — | |
| SCHEMBL14790223 | 0.78 | NPC1 (0.44) | KCNH2TAAR1KMT2ACYP2C9HDAC4 | |
| SCHEMBL31031032 | 0.76 | KMT2A (0.45) | KMT2ACYP2C9 | |
| SCHEMBL1063920 | 0.76 | CYP2C9 (0.61) | KMT2ACYP2C9USP30 | |
| SCHEMBL24409108 | 0.75 | KMT2A (0.34) | KMT2A | |
| SCHEMBL14150735 | 0.74 | KMT2A (0.64) | KMT2ACYP2C9 | |
| SCHEMBL15754423 | 0.74 | RPA1 (0.50) | KMT2ACYP2C9 | |
| SCHEMBL27082306 | 0.73 | MGLL (0.39) | USP30 | |
| SCHEMBL1816062 | 0.73 | CYP2C9 (0.45) | KMT2ACYP2C9USP30 | |
| SCHEMBL25123042 | 0.72 | ALKBH2 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117715904-A | CDK2 degrading agents and uses thereof | 凯麦拉医疗公司 | 2024-03-15 | — | — | CN | disclosed |
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |