Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 4/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27166998 | 0.77 | FFAR1 (0.47) | MTNR1AMTNR1BRAB9ANPC1FFAR1 | |
| SCHEMBL6248478 | 0.77 | ALDH1A1 (0.52) | MTNR1AMTNR1BRAB9ANPC1FFAR1 | |
| SCHEMBL23463476 | 0.76 | MTNR1A (0.48) | MTNR1AMTNR1BPKMRAB9ANPC1 | |
| SCHEMBL10401993 | 0.76 | FFAR1 (0.54) | MTNR1AMTNR1BRAB9ANPC1FFAR1 | |
| SCHEMBL10401991 | 0.74 | FFAR1 (0.52) | MTNR1AMTNR1BRAB9ANPC1FFAR1 | |
| Toluene SCHEMBL27919588 | 0.74 | GAA (0.54) | RAB9ANPC1ALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL137308 | 0.74 | LMNA (0.65) | RAB9ANPC1ALDH1A1L3MBTL1SMN1; SMN2 | |
| SCHEMBL16594277 | 0.72 | ALDH1A1 (0.43) | RAB9ANPC1FFAR1ALDH1A1L3MBTL1 | |
| SCHEMBL10874494 | 0.72 | LMNA (0.51) | MTNR1AMTNR1BPKMRAB9ANPC1 | |
| SCHEMBL16104933 | 0.72 | TDP1 (0.55) | RAB9ANPC1FFAR1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1318978-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | Abbott Laboratories (US) | 2003-06-18 | — | — | EP | disclosed |
| WO-2002024636-A2 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ABBOTT LABORATORIES (US) | 2002-03-28 | — | — | WO | disclosed |