Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS5 | Q9UNA0 | 11/20 | 0.44 |
| ▸ | MMP2 | P08253 | 4/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.36 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.35 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29135473 | 0.84 | SMARCA2 (0.46) | ADAMTS5MMP2 | |
| SCHEMBL11963066 | 0.79 | ADAMTS5 (0.45) | ADAMTS5MMP2AVPR1ASMOGRM1 | |
| SCHEMBL29668471 | 0.77 | GBA1 (0.38) | — | |
| SCHEMBL14913148 | 0.75 | GRM1 (0.40) | SMOGRM1SLC6A7 | |
| SCHEMBL25385150 | 0.74 | GAA (0.44) | ADAMTS5MMP2AVPR1ASMOGRM1 | |
| SCHEMBL28934391 | 0.74 | GAA (0.44) | ADAMTS5MMP2AVPR1ASMOGRM1 | |
| SCHEMBL25384299 | 0.74 | GAA (0.44) | ADAMTS5MMP2AVPR1ASMOGRM1 | |
| SCHEMBL11963541 | 0.73 | GFER (0.37) | ADAMTS5MMP2SMOGRM1SLC6A7 | |
| SCHEMBL11963506 | 0.73 | GRM1 (0.46) | ADAMTS5MMP2AVPR1ASMOGRM1 | |
| SCHEMBL902065 | 0.73 | GRM1 (0.46) | ADAMTS5MMP2AVPR1ASMOGRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4333982-A1 | PKC-THETA MODULATORS | Exscientia Al Limited (GB) | 2024-03-13 | — | — | EP | disclosed |