Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMARCA2 | P51531 | 1/20 | 0.46 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.46 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.43 |
| ▸ | ADAMTS5 | Q9UNA0 | 2/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27167140 | 0.84 | ADAMTS5 (0.44) | ADAMTS5MMP2 | |
| SCHEMBL24485876 | 0.82 | CKS1B (0.48) | GPR119STSMEN1KMT2AKCNH2 | |
| SCHEMBL38664512 | 0.81 | SMARCA2 (0.48) | SMARCA2SMARCA4PBRM1ABCB1GPR119 | |
| SCHEMBL17871504 | 0.81 | MMP2 (0.51) | SMARCA2SMARCA4PBRM1ABCB1GPR119 | |
| SCHEMBL17871501 | 0.81 | MMP2 (0.51) | SMARCA2SMARCA4PBRM1ABCB1GPR119 | |
| SCHEMBL30005593 | 0.81 | SMARCA2 (0.49) | SMARCA2SMARCA4PBRM1GPR119ADAMTS5 | |
| SCHEMBL30005481 | 0.81 | SMARCA2 (0.49) | SMARCA2SMARCA4PBRM1GPR119ADAMTS5 | |
| SCHEMBL22720339 | 0.80 | ABCB1 (0.45) | SMARCA2SMARCA4PBRM1ABCB1GPR119 | |
| SCHEMBL22720337 | 0.80 | ABCB1 (0.45) | SMARCA2SMARCA4PBRM1ABCB1GPR119 | |
| SCHEMBL24851280 | 0.80 | SMARCA2 (0.45) | SMARCA2SMARCA4PBRM1ABCB1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260035367-A1 | PKC-Theta Modulators | CELGENE CORPORATION (US) | 2026-02-05 | — | — | US | disclosed |
| US-20240262821-A1 | PKC-Theta Modulators | EXSCIENTIA AL LIMITED (GB) | 2024-08-08 | — | — | US | disclosed |
| EP-4333982-A1 | PKC-THETA MODULATORS | Exscientia Al Limited (GB) | 2024-03-13 | — | — | EP | disclosed |
| CN-117355522-A | PKC-theta modulators | 爱智药人工智能有限公司 | 2024-01-05 | — | — | CN | disclosed |
| WO-2022234298-A1 | PKC-THETA MODULATORS | EXSCIENTIA AI LIMITED (GB) | 2022-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260035367-A1 | PKC-Theta Modulators | PRKAR2B, PRKAR2A, PRKCD | SMARCA2 3562/4885SMARCA4 4326/4885PBRM1 2113/4885 |
| US-20240262821-A1 | PKC-Theta Modulators | PRKCQ, PRKCH, PRKCE | SMARCA2 1889/4885SMARCA4 2296/4885PBRM1 2725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.