Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PFKFB2 | O60825 | 1/20 | 0.38 |
| ▸ | PFKFB1 | P16118 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27167504 | 0.82 | GABRA1 (0.42) | GABRA1GABRB2KDM4EALDH1A1GABRB1 | |
| SCHEMBL29992349 | 0.82 | GABRA1 (0.42) | GABRA1GABRB2KDM4EALDH1A1GABRB1 | |
| SCHEMBL27167520 | 0.81 | GABRA1 (0.37) | GABRA1GABRB2KDM4EALDH1A1GABRB1 | |
| SCHEMBL1647154 | 0.81 | GABRA1 (0.43) | GABRA1GABRB2KDM4EALDH1A1GABRB1 | |
| SCHEMBL29992395 | 0.80 | GABRA1 (0.38) | GABRA1GABRB2KDM4EALDH1A1GABRB1 | |
| SCHEMBL31047174 | 0.80 | GABRA1 (0.38) | GABRA1GABRB2KDM4EALDH1A1GABRB1 | |
| SCHEMBL27167505 | 0.78 | MAOA (0.46) | KDM4EALDH1A1HPGD | |
| SCHEMBL29992457 | 0.78 | MAOA (0.46) | KDM4EALDH1A1HPGD | |
| SCHEMBL27167522 | 0.77 | XDH (0.41) | KDM4E | |
| SCHEMBL1646345 | 0.77 | SCN9A (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160299-B | Xanthine oxidase inhibitor | 江苏新元素医药科技有限公司 | 2024-08-16 | — | — | CN | disclosed |
| US-20240262808-A1 | XANTHINE OXIDASE INHIBITOR | JIANGSU ATOM BIOSCIENCE AND PHARMACEUTICAL CO., LTD. (CN) | 2024-08-08 | — | — | US | disclosed |
| EP-4335844-A1 | CLASS OF XANTHINE OXIDASE INHIBITORS | Jiangsu Atom Bioscience and Pharmaceutical Co., Ltd. (CN) | 2024-03-13 | — | — | EP | disclosed |
| CN-115160299-A | Xanthine oxidase inhibitor | 江苏新元素医药科技有限公司 | 2022-10-11 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262808-A1 | XANTHINE OXIDASE INHIBITOR | XDH, PNPO, MPO | GABRA1 2716/4885GABRB2 2841/4885KDM4E 2348/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.