SCHEMBL271676

SCHEMBL271676

CC(C)c1nc2cc([N+](=O)[O-])ccc2[nH]1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.57
KMT2A Q03164 3/20 0.57
POLB P06746 2/20 0.57
USP2 O75604 1/20 0.57
ALDH1A1 P00352 5/20 0.52
KDM4E B2RXH2 2/20 0.50
LMNA P02545 2/20 0.50
HSD17B10 Q99714 1/20 0.50
RIPK1 Q13546 1/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MAPT P10636 7/20 0.46
MAOB P27338 1/20 0.45
NOS1 P29475 1/20 0.45
GRIA1 P42261 1/20 0.45
GRIA2 P42262 1/20 0.45
GRIA3 P42263 1/20 0.45
GRIA4 P48058 1/20 0.45
NPC1 O15118 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6519411 0.88 MEN1 (0.62) MEN1KMT2APOLBUSP2ALDH1A1
SCHEMBL5104056 0.88 MEN1 (0.55) MEN1KMT2APOLBUSP2ALDH1A1
SCHEMBL10752982 0.88 MEN1 (0.55) MEN1KMT2APOLBUSP2ALDH1A1
SCHEMBL6522909 0.88 MEN1 (0.62) MEN1KMT2APOLBUSP2ALDH1A1
SCHEMBL271677 0.88 MEN1 (0.74) MEN1KMT2APOLBUSP2ALDH1A1
SCHEMBL5213709 0.85 POLB (0.57) MEN1KMT2APOLBUSP2ALDH1A1
SCHEMBL28378483 0.82 MEN1 (0.51) MEN1KMT2APOLBUSP2ALDH1A1
SCHEMBL27415790 0.82 KMT2A (0.51) MEN1KMT2APOLBUSP2ALDH1A1
SCHEMBL4328210 0.81 ALDH1A1 (0.58) MEN1KMT2APOLBALDH1A1KDM4E
SCHEMBL7035622 0.80 MEN1 (0.52) MEN1KMT2APOLBUSP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 259 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0724193-B1 Radiographic film developers containing ascorbic acid and thioether development accelerators EASTMAN KODAK CO (US) 1998-04-15 EP claimed
EP-0724193-A2 Radiographic film developers containing ascorbic acid and thioether development accelerators EASTMAN KODAK COMPANY (US) 1996-07-31 EP claimed
US-5474879-A Hydroquinone-free EASTMAN KODAK COMPANY (US) 1995-12-12 US claimed
EP-0666501-A2 Hardening developer for silver halide photography and development method EASTMAN KODAK COMPANY (US) 1995-08-09 EP claimed
US-5389502-A Black and white photography; hydroquinone and auxiliary developers, dialdehyde hardeners, antifoggants, sulfites, oligomeric carboxyl sequestering agents EASTMAN KODAK COMPANY (US) 1995-02-14 US claimed
US-10729738-B2 Hindered disulfide drug conjugates GENENTECH, INC. (US) 2020-08-04 US disclosed
US-20170112891-A1 HINDERED DISULFIDE DRUG CONJUGATES GENENTECH INC (US) 2017-04-27 US disclosed
US-20170112891-A1 HINDERED DISULFIDE DRUG CONJUGATES GENENTECH INC (US) 2017-04-27 US disclosed
US-9000309-B2 Electromagnetic shielding film FUJIFILM CORPORATION (JP) 2015-04-07 US disclosed
US-20140234760-A1 TRANSLUCENT ELECTROMAGNETIC SHIELD FILM, PRODUCING METHOD THEREFOR AND EMULSIFIER FUJIFILM CORPORATION (JP) 2014-08-21 US disclosed
CN-101270493-B Method and apparatus for producing conductive material FUJI PHOTO FILM CO LTD 2014-02-19 CN disclosed
US-8426749-B2 Electromagnetic shielding film and optical filter FUJIFILM CORPORATION (JP) 2013-04-23 US disclosed
WO-1996004270-A1 NOVEL BENZIMIDAZOLE DERIVATIVES SYNAPTIC PHARMACEUTICAL CORPORATION (US) 1996-02-15 WO disclosed
US-5474879-A Hydroquinone-free EASTMAN KODAK COMPANY (US) 1995-12-12 US disclosed
EP-0666501-A2 Hardening developer for silver halide photography and development method EASTMAN KODAK COMPANY (US) 1995-08-09 EP disclosed
US-5419997-A After exposure in a developing solution of hydroquinone, a pyrazolone, a sulfite, a hydrazine compound and an ascorbic acid compound FUJI PHOTO FILM CO., LTD. (JP) 1995-05-30 US disclosed
US-5389502-A Black and white photography; hydroquinone and auxiliary developers, dialdehyde hardeners, antifoggants, sulfites, oligomeric carboxyl sequestering agents EASTMAN KODAK COMPANY (US) 1995-02-14 US disclosed
US-5385811-A Developers containing a 2-mercapto-3-hydroxypyrimidine and a carbonyl- and double bond-containing heterocyclic compound; antisoilants; antismudging agents; high-speed automatic processing FUJI PHOTO FILM CO., LTD. (JP) 1995-01-31 US disclosed
US-4810622-A STABILITY FUJI PHOTO FILM, CO. LTD. (JP) 1989-03-07 US disclosed
US-4672025-A BLACK AND WHITE PHOTOGRAPHIC DEVELOPER CONTAINING A CHELATING AGENT; AUTOMATIC PROCESSING FUJI PHOTO FILM CO., LTD. (JP) 1987-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10729738-B2 Hindered disulfide drug conjugates STS, TST, SCLY MEN1 3496/4885KMT2A 3040/4885POLB 4810/4885
US-20170112891-A1 HINDERED DISULFIDE DRUG CONJUGATES STS, TST, SCLY MEN1 3496/4885KMT2A 3040/4885POLB 4810/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.