SCHEMBL2717141

SCHEMBL2717141

CCN(Cc1cccs1)C(=O)CCc1cccc(C)c1

nearest known ligand 0.76

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPM8 Q7Z2W7 19/20 0.76
POLB P06746 1/20 0.51
TDP1 Q9NUW8 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30582780 1.00 TRPM8 (0.76) TRPM8POLBTDP1
SCHEMBL30582882 0.87 TRPM8 (0.67) TRPM8POLBTDP1
SCHEMBL2717606 0.87 TRPM8 (0.67) TRPM8POLBTDP1
SCHEMBL2720132 0.86 TRPM8 (1.00) TRPM8POLBTDP1
SCHEMBL10168206 0.86 TRPM8 (0.81) TRPM8POLBTDP1
SCHEMBL17230199 0.85 TRPM8 (0.65) TRPM8TDP1
SCHEMBL2720276 0.81 TRPM8 (0.80) TRPM8POLBTDP1
SCHEMBL2729613 0.80 TRPM8 (0.67) TRPM8POLBTDP1
SCHEMBL30582819 0.80 TRPM8 (0.67) TRPM8POLBTDP1
SCHEMBL2720801 0.79 TRPM8 (0.76) TRPM8POLBTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025132323-A1 COMPOSITIONS COMPRISING A SUNSCREEN ACTIVE AGENT DSM-FIRMENICH AG (CH) 2025-06-26 WO disclosed
EP-3470407-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2024-01-24 EP disclosed
CN-109414048-B Coated yeast formulation 弗门尼舍有限公司 2023-09-01 CN disclosed
US-11234450-B2 Preparations having a cooling effect SYMRISE AG (DE) 2022-02-01 US disclosed
EP-3478089-B1 PLATED YEAST FORMULATIONS FIRMENICH & CIE (CH) 2021-11-03 EP disclosed
US-11160894-B2 Perfume emanating device FIRMENICH SA (CH) 2021-11-02 US disclosed
US-11091734-B2 Plated yeast formulations FIRMENICH SA (CH) 2021-08-17 US disclosed
US-10953007-B2 Compounds useful as modulators of TRPM8 FIRMENICH INCORPORATED (US) 2021-03-23 US disclosed
US-10953007-B2 Compounds useful as modulators of TRPM8 FIRMENICH INCORPORATED (US) 2021-03-23 US disclosed
EP-3478089-A1 PLATED YEAST FORMULATIONS Firmenich SA (CH) 2019-05-08 EP disclosed
US-9394287-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2016-07-19 US disclosed
US-9394287-B2 Compounds useful as modulators of TRPM8 SENOMYX, INC. (US) 2016-07-19 US disclosed
US-20150313820-A1 PREPARATIONS SYMRISE AG (DE) 2015-11-05 US disclosed
US-20150313820-A1 PREPARATIONS SYMRISE AG (DE) 2015-11-05 US disclosed
US-20130324557-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2013-12-05 US disclosed
EP-2635572-A2 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 Senomyx, Inc. (US) 2013-09-11 EP disclosed
WO-2012061698-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-09-13 WO disclosed
WO-2012061698-A9 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-09-13 WO disclosed
WO-2012061698-A2 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-05-10 WO disclosed
WO-2012061698-A2 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 SENOMYX, INC. (US) 2012-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11160894-B2 Perfume emanating device DPM1, SURF4, FAAH2 TRPM8 151/4885POLB 936/4885TDP1 2560/4885
US-10953007-B2 Compounds useful as modulators of TRPM8 TRPM8, TRPM7, TRPM6 TRPM8 1/4885POLB 4439/4885TDP1 2867/4885
US-11234450-B2 Preparations having a cooling effect CRAT, CPT2, CPT1A TRPM8 60/4885POLB 1521/4885TDP1 3608/4885
US-20130324557-A1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 TRPM8, TRPM7, TRPM6 TRPM8 1/4885POLB 4439/4885TDP1 2867/4885
US-20150313820-A1 PREPARATIONS CRAT, ACAT2, TAS2R50 TRPM8 101/4885POLB 1657/4885TDP1 4520/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.