Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 15/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17230199 | 0.87 | TRPM8 (0.65) | TRPM8TSHRTDP1MEN1KMT2A | |
| SCHEMBL2720132 | 0.86 | TRPM8 (1.00) | TRPM8TDP1POLB | |
| SCHEMBL10168206 | 0.86 | TRPM8 (0.81) | TRPM8TDP1POLB | |
| SCHEMBL2720276 | 0.85 | TRPM8 (0.80) | TRPM8TDP1POLB | |
| SCHEMBL6122118 | 0.83 | TRPM8 (0.60) | TRPM8LMNAHPGDTSHRTDP1 | |
| SCHEMBL2719417 | 0.83 | TRPM8 (1.00) | TRPM8 | |
| SCHEMBL2717141 | 0.79 | TRPM8 (0.76) | TRPM8TDP1POLB | |
| SCHEMBL30582780 | 0.79 | TRPM8 (0.76) | TRPM8TDP1POLB | |
| SCHEMBL2717606 | 0.78 | TRPM8 (0.67) | TRPM8TDP1POLB | |
| SCHEMBL30582882 | 0.78 | TRPM8 (0.67) | TRPM8TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118697922-A | Perfume dispersing device | 弗门尼舍有限公司 | 2024-09-27 | — | — | CN | disclosed |
| EP-3470407-B1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | FIRMENICH INCORPORATED (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-109414048-B | Coated yeast formulation | 弗门尼舍有限公司 | 2023-09-01 | — | — | CN | disclosed |
| US-11234450-B2 | Preparations having a cooling effect | SYMRISE AG (DE) | 2022-02-01 | — | — | US | disclosed |
| EP-3478089-B1 | PLATED YEAST FORMULATIONS | FIRMENICH & CIE (CH) | 2021-11-03 | — | — | EP | disclosed |
| US-11160894-B2 | Perfume emanating device | FIRMENICH SA (CH) | 2021-11-02 | — | — | US | disclosed |
| US-11091734-B2 | Plated yeast formulations | FIRMENICH SA (CH) | 2021-08-17 | — | — | US | disclosed |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-23 | — | — | US | disclosed |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | FIRMENICH INCORPORATED (US) | 2021-03-23 | — | — | US | disclosed |
| EP-3478089-A1 | PLATED YEAST FORMULATIONS | Firmenich SA (CH) | 2019-05-08 | — | — | EP | disclosed |
| US-9394287-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-9394287-B2 | Compounds useful as modulators of TRPM8 | SENOMYX, INC. (US) | 2016-07-19 | — | — | US | disclosed |
| US-20150313820-A1 | PREPARATIONS | SYMRISE AG (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20150313820-A1 | PREPARATIONS | SYMRISE AG (DE) | 2015-11-05 | — | — | US | disclosed |
| US-20130324557-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2013-12-05 | — | — | US | disclosed |
| EP-2635572-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | Senomyx, Inc. (US) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A9 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-09-13 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
| WO-2012061698-A2 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | SENOMYX, INC. (US) | 2012-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11160894-B2 | Perfume emanating device | DPM1, SURF4, FAAH2 | TRPM8 151/4885LMNA 3524/4885HPGD 390/4885 |
| US-10953007-B2 | Compounds useful as modulators of TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885LMNA 4155/4885HPGD 1694/4885 |
| US-11234450-B2 | Preparations having a cooling effect | CRAT, CPT2, CPT1A | TRPM8 60/4885LMNA 1034/4885HPGD 2629/4885 |
| US-20130324557-A1 | COMPOUNDS USEFUL AS MODULATORS OF TRPM8 | TRPM8, TRPM7, TRPM6 | TRPM8 1/4885LMNA 4155/4885HPGD 1694/4885 |
| US-20150313820-A1 | PREPARATIONS | CRAT, ACAT2, TAS2R50 | TRPM8 101/4885LMNA 1435/4885HPGD 2263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.