Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 10/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13949382 | 0.98 | OPRM1 (0.36) | OPRM1OPRD1ADORA1OPRK1ABCB11 | |
| Hydrochloric Acid SCHEMBL26124624 | 0.97 | ADORA1 (0.37) | OPRM1OPRD1ADORA1OPRK1ABCB11 | |
| SCHEMBL26870653 | 0.82 | MAPT (0.36) | MEN1KMT2AMAPTKDM4EALOX15 | |
| SCHEMBL30818832 | 0.80 | MAPT (0.35) | OPRM1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL24870690 | 0.80 | ADORA1 (0.40) | OPRM1OPRD1ADORA1OPRK1MEN1 | |
| SCHEMBL2864246 | 0.79 | GLO1 (0.37) | OPRM1OPRD1ADORA1OPRK1MEN1 | |
| Hydrochloric Acid SCHEMBL3547234 | 0.77 | ADORA1 (0.38) | OPRM1OPRD1ADORA1OPRK1MEN1 | |
| SCHEMBL3881844 | 0.77 | TSHR (0.41) | MEN1KMT2AMAPTKDM4ELMNA | |
| SCHEMBL14539579 | 0.77 | ALOX15 (0.39) | OPRM1OPRD1ADORA1OPRK1MEN1 | |
| SCHEMBL13814955 | 0.73 | ALDH1A1 (0.36) | OPRM1OPRD1ADORA1OPRK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336596-A1 | PARP7 INHIBITOR AND USE THEREOF | NOVOSTAR PHARMACEUTICALS, LTD. (CN) | 2024-10-10 | — | — | US | disclosed |
| EP-4338737-A1 | PARP7 INHIBITOR AND USE THEREOF | Novostar Pharmaceuticals, Ltd. (CN) | 2024-03-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336596-A1 | PARP7 INHIBITOR AND USE THEREOF | PARP1, PARP3, PARP11 | OPRM1 3404/4885OPRD1 2802/4885ADORA1 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.