Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Syringic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.85 |
| ▸ | CA12 | O43570 | 2/20 | 0.85 |
| ▸ | CA1 | P00915 | 2/20 | 0.85 |
| ▸ | CA2 | P00918 | 2/20 | 0.85 |
| ▸ | CA4 | P22748 | 2/20 | 0.85 |
| ▸ | CA6 | P23280 | 2/20 | 0.85 |
| ▸ | CA7 | P43166 | 2/20 | 0.85 |
| ▸ | CA9 | Q16790 | 2/20 | 0.85 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.85 |
| ▸ | CA3 | P07451 | 1/20 | 0.85 |
| ▸ | CA5A | P35218 | 1/20 | 0.85 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.85 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TPMT | P51580 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Syringic Acid SCHEMBL42751 | 0.92 | CA12 (1.00) | PKMCA12CA1CA2CA4 | |
| Syringic Acid SCHEMBL27602358 | 0.92 | CA12 (1.00) | PKMCA12CA1CA2CA4 | |
| Syringic Acid SCHEMBL30250854 | 0.90 | PKM (0.96) | PKMCA12CA1CA2CA4 | |
| Syringic Acid SCHEMBL27832093 | 0.90 | PKM (0.96) | PKMCA12CA1CA2CA4 | |
| Syringic Acid SCHEMBL1356555 | 0.86 | PKM (0.88) | PKMCA12CA1CA2CA4 | |
| Syringic Acid SCHEMBL17275054 | 0.85 | CA12 (0.85) | PKMCA12CA1CA2CA4 | |
| Syringic Acid SCHEMBL6072775 | 0.85 | PTGS2 (0.92) | PKMCA12CA1CA2CA4 | |
| SCHEMBL975675 | 0.84 | PTGS2 (1.00) | PKMCA12CA1CA2CA4 | |
| SCHEMBL30615314 | 0.84 | PTGS2 (1.00) | PKMCA12CA1CA2CA4 | |
| SCHEMBL13671457 | 0.83 | PKM (0.75) | PKMCA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240090537-A1 | Nanoencapsulation of Jania rubens seaweeds' antioxidants for food applications | THE AMERICAN UNIVERSITY IN CAIRO | 2024-03-21 | — | — | US | disclosed |