SCHEMBL975675

SCHEMBL975675

COc1cc(C(=O)O)cc(O)c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 1.00
CA12 O43570 3/20 0.84
CA1 P00915 3/20 0.84
CA2 P00918 3/20 0.84
CA4 P22748 3/20 0.84
CA6 P23280 3/20 0.84
CA7 P43166 3/20 0.84
CA9 Q16790 3/20 0.84
CA14 Q9ULX7 3/20 0.84
CA3 P07451 2/20 0.84
CA5A P35218 2/20 0.84
CA5B Q9Y2D0 2/20 0.84
PKM P14618 1/20 0.84
TPMT P51580 5/20 0.72
LMNA P02545 4/20 0.64
MAPK1 P28482 2/20 0.64
KDM4E B2RXH2 2/20 0.64
FUT7 Q11130 2/20 0.64
TDP1 Q9NUW8 2/20 0.64
ALDH1A1 P00352 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30615314 1.00 PTGS2 (1.00) PTGS2CA12CA1CA2CA4
Syringic Acid SCHEMBL6072775 0.96 PTGS2 (0.92) PTGS2CA12CA1CA2CA4
Syringic Acid SCHEMBL42751 0.91 CA12 (1.00) PTGS2CA12CA1CA2CA4
Syringic Acid SCHEMBL27602358 0.91 CA12 (1.00) PTGS2CA12CA1CA2CA4
SCHEMBL29913216 0.91 PTGS2 (0.83) PTGS2CA12CA1CA2CA4
SCHEMBL22824549 0.91 PTGS2 (0.83) PTGS2CA12CA1CA2CA4
SCHEMBL24614012 0.89 POLB (0.81) PTGS2CA12CA1CA2CA4
Syringic Acid SCHEMBL27832093 0.89 PKM (0.96) PTGS2CA12CA1CA2CA4
Syringic Acid SCHEMBL30250854 0.89 PKM (0.96) PTGS2CA12CA1CA2CA4
SCHEMBL6072772 0.88 POLB (0.78) PTGS2CA12CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 507 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125731-A1 MICROORGANISMS AND METHODS FOR PRODUCING CAROTENOIDS AND OTHER COMPOUNDS WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2026-05-07 US claimed
EP-4168255-B1 ELASTOMERIC COMPOSITION COMPRISING A PHENOLIC COMPOUND AND A COMPOUND FROM THE MONOSACCHARIDE FAMILY MICHELIN & CIE (FR) 2026-03-04 EP claimed
CN-120022318-A Application of white leaf single cluster tea and active ingredients thereof in uric acid reduction 华南农业大学 2025-05-23 CN claimed
US-12163004-B2 Polymer composites WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC (US) 2024-12-10 US claimed
CN-119081041-A Polyacetal prepared from formaldehyde and anhydride by copolymerization and preparation method thereof 浙江大学 2024-12-06 CN claimed
US-20240350574-A1 PHENOLIC PHYTOCHEMICALS FOR BONE METASTASIS OF CANCER NDSU RESEARCH FOUNDATION 2024-10-24 US claimed
US-12076316-B2 Levorphanol prodrugs and processes for making and using them ZEVRA THERAPEUTICS INC. 2024-09-03 US claimed
US-11807873-B2 Conversion of S-lignin compounds to useful intermediates ALLIANCE FOR SUSTAINABLE ENERGY, LLC (US) 2023-11-07 US claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
EP-4230201-A1 COMPOSITION FOR TREATING NEURODEGENERATIVE DISEASES UNIVERSIDADE NOVA DE LISBOA (PT) 2023-08-23 EP claimed
US-20130150395-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF KEMPHARM, INC. (US) 2013-06-13 US claimed
WO-2013063204-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF KEMPHARM, INC. (US) 2013-05-02 WO claimed
WO-2013016668-A2 METHYLPHENIDATE-PRODRUGS, PROCESSES OF MAKING AND USING THE SAME KEMPHARM INC. (US) 2013-01-31 WO claimed
US-20120142719-A1 Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof ALTER DOMUS (US) LLC 2012-06-07 US claimed
CN-102480959-A Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof KEMPHARM INC 2012-05-30 CN claimed
US-20120123171-A1 Catalytic reduction of lignin acids and substituted aliphatic carboxylic acid compounds CARTER TECHNOLOGIES (US) 2012-05-17 US claimed
EP-2448407-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF Kempharm, Inc. (US) 2012-05-09 EP claimed
US-20110002990-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF ALTER DOMUS (US) LLC 2011-01-06 US claimed
EP-1157693-A1 USE OF EPIGALLOCATECHIN 3-O-(3-O-METHYL) GALLATE AND/OR EPIGALLOCATECHIN 3-O-(4-O-METHYL) GALLATE FOR THE TREATMENT OF ALLERGY AND/OR INFLAMMATION National Agricultural Research Organisation (NARO) (JP) 2001-11-28 EP claimed
US-4756950-A Support, heat meltable ink layer comprising dye, saturated polyester MITSUBISHI PAPER MILLS, LTD. (JP) 1988-07-12 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12076316-B2 Levorphanol prodrugs and processes for making and using them OPRM1, OPRL1, OPRK1 PTGS2 1209/4885CA12 1814/4885CA1 1503/4885
US-20260125731-A1 MICROORGANISMS AND METHODS FOR PRODUCING CAROTENOIDS AND OTHER COMPOUNDS DHPS, DCXR, BLVRB PTGS2 541/4885CA12 3361/4885CA1 3604/4885
US-20110002990-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROCODONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF CYP2B6, CYP3A43, CYP2D6 PTGS2 599/4885CA12 2215/4885CA1 1685/4885
US-20120142719-A1 Benzoic acid, benzoic acid derivatives and heteroaryl carboxylic acid conjugates of hydrocodone, prodrugs, methods of making and use thereof CYP2B6, CYP3A43, CYP2D6 PTGS2 599/4885CA12 2215/4885CA1 1685/4885
US-20130150395-A1 BENZOIC ACID, BENZOIC ACID DERIVATIVES AND HETEROARYL CARBOXYLIC ACID CONJUGATES OF HYDROMORPHONE, PRODRUGS, METHODS OF MAKING AND USE THEREOF OPRM1, OPRK1, CYP2D6 PTGS2 850/4885CA12 1872/4885CA1 1329/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.