Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29258838 | 1.00 | HCAR3 (0.43) | HCAR3KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL27176929 | 0.91 | KDM4E (0.42) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL30966515 | 0.88 | ALDH1A1 (0.47) | HCAR3KDM4EHPGDKMT2AALDH1A1 | |
| SCHEMBL30269431 | 0.85 | KDM4E (0.50) | KDM4EHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL29157314 | 0.85 | HCAR3 (0.46) | HCAR3KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL29157312 | 0.85 | HCAR3 (0.46) | HCAR3KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL27205413 | 0.84 | HCAR3 (0.39) | HCAR3KDM4EHPGDKMT2AALDH1A1 | |
| SCHEMBL27176958 | 0.84 | HCAR3 (0.39) | HCAR3KDM4EHPGDKMT2AALDH1A1 | |
| SCHEMBL29170127 | 0.82 | HCAR3 (0.53) | HCAR3KDM4EHPGDKMT2AMEN1 | |
| SCHEMBL29170125 | 0.82 | HCAR3 (0.53) | HCAR3KDM4EHPGDKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344349-A | 4-Alkoxybenzimidazole-6-carboxylic acid derivatives as GLP-1 receptor agonists | 中国科学院上海药物研究所 | 2024-07-16 | — | — | CN | disclosed |
| CN-118103366-A | Certain 2, 5-diazabicyclo [4.2.0] octanes as GLP-1 receptor modulators | 阿斯利康(瑞典)有限公司 | 2024-05-28 | — | — | CN | disclosed |