SCHEMBL2719218

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2719361	0.82	PPARG (0.53)	NPC1RAB9ARXFP1NPSR1KDM4E
	SCHEMBL3805118	0.81	RAB9A (0.60)	NPC1RAB9ARXFP1NPSR1KDM4E
	SCHEMBL14648292	0.80	RAB9A (0.55)	NPC1RAB9ARXFP1NPSR1KDM4E
	SCHEMBL30581235	0.77	KDM4E (1.00)	NPC1RAB9ARXFP1NPSR1KDM4E
	SCHEMBL29076101	0.77	KDM4E (1.00)	NPC1RAB9ARXFP1NPSR1KDM4E
	SCHEMBL2972386	0.76	NPC1 (0.54)	NPC1RAB9ARXFP1NPSR1KDM4E
	SCHEMBL31448481	0.74	KDM4E (0.70)	NPC1RAB9ARXFP1NPSR1KDM4E
	SCHEMBL2879788	0.74	KDM4E (0.66)	NPC1RAB9ANPSR1KDM4ESMN1; SMN2
	SCHEMBL2719970	0.74	KDM4E (0.64)	NPC1RAB9ARXFP1NPSR1KDM4E
	SCHEMBL8418773	0.74	ALDH1A1 (0.78)	RAB9ANPSR1KDM4ESMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.