Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL276976 | 0.98 | MCL1 (0.46) | MCL1MAPTKDM4EMRGPRX4ALDH1A1 | |
| SCHEMBL270420 | 0.83 | ALDH1A1 (0.44) | MCL1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2375905 | 0.82 | KDM4E (0.45) | MCL1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL271654 | 0.82 | ALDH1A1 (0.43) | MCL1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2375898 | 0.82 | ALDH1A1 (0.43) | MCL1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL2906179 | 0.80 | CES2 (0.47) | MRGPRX4CYP3A4FLT1FLT4KDR | |
| SCHEMBL2928941 | 0.79 | ACLY (0.39) | MAPTMRGPRX4 | |
| SCHEMBL13846826 | 0.78 | KDM4E (0.45) | MCL1MAPTKDM4EALDH1A1MEN1 | |
| SCHEMBL27474700 | 0.78 | FLT1 (0.40) | MAPTALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL14426968 | 0.77 | CYP3A4 (0.41) | MCL1MAPTKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |