SCHEMBL27199679

SCHEMBL27199679

CC1=Cc2c(cc3c(c2-c2cc(C(C)(C)C)cc(C(C)(C)C)c2)CCC3)C1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27171026 0.92
SCHEMBL29595700 0.88 FGF23 (0.32) MEN1KMT2A
SCHEMBL22776383 0.88 FGF23 (0.32) MEN1KMT2A
SCHEMBL23014216 0.88 IKBKB (0.33) MEN1KMT2A
SCHEMBL29853888 0.88 IKBKB (0.33) MEN1KMT2A
SCHEMBL20240183 0.81 PTGS2 (0.33)
SCHEMBL17180472 0.81 MEN1 (0.31) MEN1KMT2A
SCHEMBL27171020 0.81 FGF23 (0.30)
SCHEMBL3697443 0.80 BRD4 (0.35) MEN1KMT2A
SCHEMBL29596409 0.80 BRD4 (0.35) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114401977-B Transition metal compound and catalyst composition comprising the same 株式会社LG化学 2024-08-02 CN disclosed
US-20240124618-A1 Asymmetric Constrained Geometry Catalysts EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-04-18 US disclosed
EP-4271718-A1 POLYOLEFIN-BASED IONOMERS AND PRODUCTION THEREOF ExxonMobil Chemical Patents Inc. (US) 2023-11-08 EP disclosed
CN-113614119-B Hybrid supported metallocene catalyst and method for preparing polypropylene using the same 株式会社LG化学 2023-04-11 CN disclosed
WO-2022146634-A1 POLYOLEFIN-BASED IONOMERS AND PRODUCTION THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2022-07-07 WO disclosed
CN-114401977-A Transition metal compound and catalyst composition comprising the same 株式会社LG化学 2022-04-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240124618-A1 Asymmetric Constrained Geometry Catalysts GNE, ESR1, PGR MEN1 2998/4885KMT2A 1932/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.