Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2788605 | 0.92 | LMNA (0.55) | LMNAHPGDKDM4ESMN1; SMN2TDP1 | |
| SCHEMBL28575157 | 0.90 | CNR2 (0.54) | LMNAALDH1A1TDP1TSHRESR1 | |
| SCHEMBL28633934 | 0.89 | KDM4E (0.56) | LMNAHPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL794412 | 0.87 | KMT2A (0.62) | LMNAHPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL16253498 | 0.85 | LMNA (0.49) | LMNAHPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL24983859 | 0.84 | HPGD (0.57) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL30141079 | 0.84 | HPGD (0.57) | LMNAHPGDSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2338199 | 0.83 | HPGD (0.76) | LMNAHPGDKDM4ESMN1; SMN2NPC1 | |
| SCHEMBL13385885 | 0.83 | TP53 (0.48) | TSHR | |
| SCHEMBL16491058 | 0.81 | TSHR (0.51) | LMNAHPGDKDM4ESMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192749-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-06-22 | — | — | US | disclosed |
| US-11578093-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2023-02-14 | — | — | US | disclosed |
| US-20210147465-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2021-05-20 | — | — | US | disclosed |
| US-10800805-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-10-13 | — | — | US | disclosed |
| US-10787573-B2 | Multimeric protected fluorescent reagents | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2020-09-29 | — | — | US | disclosed |
| US-9957291-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| US-9957291-B2 | Protected fluorescent reagent compounds | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-05-01 | — | — | US | disclosed |
| EP-2528604-B1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2017-11-22 | — | — | EP | disclosed |
| US-20160237279-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-20160237279-A1 | MULTIMERIC PROTECTED FLUORESCENT REAGENTS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2016-08-18 | — | — | US | disclosed |
| US-20160200683-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | UNIV CALIFORNIA (US) | 2016-07-14 | — | — | US | disclosed |
| US-9296693-B2 | Acyl piperidine inhibitors of soluble epoxide hydrolase | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-03-29 | — | — | US | disclosed |
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2015-02-19 | — | — | US | disclosed |
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. | 2015-02-19 | — | — | US | disclosed |
| US-20130143925-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-06-06 | — | — | US | disclosed |
| EP-2528604-A2 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | The Regents of The University of California (US) | 2012-12-05 | — | — | EP | disclosed |
| WO-2012054093-A2 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-04-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150050659-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | LMNA 108/4885HPGD 3592/4885KDM4E 4187/4885 |
| US-11578093-B2 | Protected fluorescent reagent compounds | ERCC4, ERCC2, ERCC1 | LMNA 108/4885HPGD 3592/4885KDM4E 4187/4885 |
| US-10800805-B2 | Protected fluorescent reagent compounds | ERCC4, ERCC2, ERCC1 | LMNA 108/4885HPGD 3592/4885KDM4E 4187/4885 |
| US-20230192749-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | LMNA 108/4885HPGD 3592/4885KDM4E 4187/4885 |
| US-20130143925-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | EPHX1, FAAH, FAAH2 | LMNA 4284/4885HPGD 71/4885KDM4E 921/4885 |
| US-20210147465-A1 | PROTECTED FLUORESCENT REAGENT COMPOUNDS | ERCC4, ERCC2, ERCC1 | LMNA 108/4885HPGD 3592/4885KDM4E 4187/4885 |
| US-20160200683-A1 | ACYL PIPERIDINE INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE | EPHX1, FAAH, FAAH2 | LMNA 4284/4885HPGD 71/4885KDM4E 921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.