Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 3/20 | 0.63 |
| ▸ | WNT3A | P56704 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA4 | P22748 | 1/20 | 0.53 |
| ▸ | CA6 | P23280 | 1/20 | 0.53 |
| ▸ | CA7 | P43166 | 1/20 | 0.53 |
| ▸ | TPMT | P51580 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5355533 | 1.00 | CTNNB1 (0.63) | CTNNB1WNT3AMAPTTSHRCYP1A2 | |
| SCHEMBL9119840 | 0.98 | CTNNB1 (0.65) | CTNNB1WNT3AMAPTTSHRCYP1A2 | |
| SCHEMBL31556194 | 0.94 | CTNNB1 (0.71) | CTNNB1WNT3AMAPTTSHRCYP1A2 | |
| SCHEMBL31556192 | 0.92 | CTNNB1 (0.73) | CTNNB1WNT3AMAPTTSHRCYP1A2 | |
| SCHEMBL14483927 | 0.89 | CTNNB1 (0.69) | CTNNB1WNT3AMAPTTSHRCYP1A2 | |
| SCHEMBL9588048 | 0.88 | THRA (0.66) | CTNNB1WNT3ATHRATHRBPDE4B | |
| SCHEMBL7389336 | 0.87 | HTT (0.56) | CTNNB1WNT3AMAPTALDH1A1ACHE | |
| SCHEMBL9558246 | 0.87 | HPGD (0.50) | CTNNB1WNT3ACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL7393792 | 0.87 | POLB (0.49) | CTNNB1WNT3AMAPTALDH1A1POLB | |
| SCHEMBL11612755 | 0.86 | CTNNB1 (0.61) | CTNNB1WNT3AMAPTTSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240300987-A1 | TRAP1 INHIBITOR AND USE THEREOF | UNIST (ULSAN NATIONAL INSTITUTE OF SCIENCE AND TECHNOLOGY) (KR) | 2024-09-12 | — | — | US | disclosed |
| EP-4357351-A1 | TRAP1 INHIBITOR AND USE THEREOF | Smartin Bio Inc. (KR) | 2024-04-24 | — | — | EP | disclosed |
| CN-117769559-A | TRAP1 inhibitors and uses thereof | 斯玛特恩生物公司 | 2024-03-26 | — | — | CN | disclosed |
| WO-2022265178-A1 | TRAP1 INHIBITOR AND USE THEREOF | 주식회사 스마틴바이오 | 2022-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240300987-A1 | TRAP1 INHIBITOR AND USE THEREOF | TRAP1, PPP1R7, PPP1R15A | CTNNB1 3668/4885WNT3A 3550/4885MAPT 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.