Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27200607 | 0.85 | NPC1 (0.39) | KMT2AOPRK1MAPTHTTRXFP1 | |
| SCHEMBL6605377 | 0.79 | ALDH1A1 (0.48) | KMT2AMAPTHTTRXFP1ALDH1A1 | |
| SCHEMBL22926818 | 0.78 | KDM4E (0.44) | KMT2AMAPTHTTALDH1A1MEN1 | |
| SCHEMBL22927056 | 0.76 | ALDH1A1 (0.41) | KMT2AMAPTHTTRXFP1ALDH1A1 | |
| SCHEMBL23702621 | 0.76 | KMT2A (0.50) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL4470507 | 0.75 | ALDH1A1 (0.45) | KMT2AMAPTHTTRXFP1ALDH1A1 | |
| SCHEMBL30111820 | 0.73 | KMT2A (0.47) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL5909894 | 0.73 | MAPT (0.46) | MAPTHTTRXFP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4033934 | 0.71 | PDE7A (0.51) | KMT2AMAPTALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL516896 | 0.71 | ALDH1A1 (0.51) | NPBWR1KMT2AOPRK1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003976-B1 | PICOLINAMIDE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | GLOBACHEM NV (BE) | 2024-04-24 | — | — | EP | disclosed |
| US-20220256855-A1 | PICOLINAMIDE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | GLOBACHEM NV (BE) | 2022-08-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220256855-A1 | PICOLINAMIDE DERIVATIVES USEFUL AS AGRICULTURAL FUNGICIDES | FKBP2, FKBP14, FKBP1A | NPBWR1 2486/4885KMT2A 3034/4885OPRK1 4879/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.