Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 19/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL270665 | 0.91 | BMP1 (0.38) | NR1H2NR1H3 | |
| SCHEMBL272431 | 0.90 | P2RX7 (0.40) | NR1H2NR1H3P2RX7 | |
| SCHEMBL271720 | 0.89 | SCD (0.35) | P2RX7 | |
| SCHEMBL271470 | 0.88 | NFE2L2 (0.33) | NR1H2NR1H3 | |
| SCHEMBL271591 | 0.88 | RORC (0.37) | NR1H2NR1H3 | |
| SCHEMBL272015 | 0.86 | MRGPRX4 (0.36) | P2RX7 | |
| SCHEMBL271791 | 0.85 | P2RX7 (0.35) | P2RX7 | |
| SCHEMBL271420 | 0.84 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL269838 | 0.83 | POLQ (0.38) | — | |
| SCHEMBL271739 | 0.83 | MAPT (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| EP-2220056-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009063180-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | NR1H2 1260/4885NR1H3 1422/4885P2RX7 1479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.