Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 7/20 | 0.51 |
| ▸ | HTR2A | P28223 | 7/20 | 0.51 |
| ▸ | HTR2C | P28335 | 5/20 | 0.51 |
| ▸ | HTR2B | P41595 | 3/20 | 0.51 |
| ▸ | HTR6 | P50406 | 6/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.46 |
| ▸ | HTR7 | P34969 | 5/20 | 0.43 |
| ▸ | HTR1B | P28222 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | CDK4 | P11802 | 2/20 | 0.43 |
| ▸ | CCND1 | P24385 | 2/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885251 | 1.00 | HTR1A (0.51) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL30885219 | 0.77 | HTR2A (0.55) | HTR1AHTR2AHTR6HTR7DRD2 | |
| SCHEMBL27201256 | 0.77 | HTR2A (0.55) | HTR1AHTR2AHTR6HTR7DRD2 | |
| SCHEMBL602649 | 0.71 | HRH3 (0.42) | HTR2BHTR1B | |
| SCHEMBL20970876 | 0.70 | HTR2A (0.71) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL29403614 | 0.70 | HTR2A (0.71) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL8861727 | 0.70 | HTR2A (0.76) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| N,N-Dimethyltryptamine SCHEMBL29350959 | 0.70 | HTR2A (1.00) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| N,N-Dimethyltryptamine SCHEMBL335710 | 0.70 | HTR2A (1.00) | HTR1AHTR2AHTR2CHTR2BHTR6 | |
| SCHEMBL30896267 | 0.70 | HTR2A (0.81) | HTR1AHTR2AHTR2CHTR2BHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-25 | — | — | US | claimed |
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-25 | — | — | US | disclosed |
| US-20170221996-A1 | GRAPHENE-BASED LAMINATE AND METHOD OF PREPARING THE SAME | HANWHA TECHWIN CO., LTD. (KR) | 2017-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | GID4, MDM2, XIAP | HTR1A 3418/4885HTR2A 3413/4885HTR2C 2974/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.