Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 13/20 | 0.55 |
| ▸ | HTR1A | P08908 | 12/20 | 0.55 |
| ▸ | HTR6 | P50406 | 12/20 | 0.55 |
| ▸ | DRD2 | P14416 | 11/20 | 0.55 |
| ▸ | HTR7 | P34969 | 11/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MC5R | P33032 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | MC1R | Q01726 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885219 | 1.00 | HTR2A (0.55) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL28043713 | 0.80 | HTR1A (0.53) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL15756990 | 0.77 | NUDT1 (0.53) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL30885251 | 0.77 | HTR1A (0.51) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL27201422 | 0.77 | HTR1A (0.51) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL30579299 | 0.73 | KMT2A (0.51) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL20557937 | 0.73 | KMT2A (0.51) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL31535625 | 0.73 | KMT2A (0.59) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL7110415 | 0.73 | HTR1A (0.48) | HTR2AHTR1AHTR6DRD2HTR7 | |
| SCHEMBL2732463 | 0.70 | HTR2A (0.69) | HTR2AHTR1AHTR6HTR7KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-25 | — | — | US | claimed |
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | ACCUTAR BIOTECHNOLOGY INC. (US) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132464-A1 | HETEROCYCLIC COMPOUNDS AS E3 LIGASE INHIBITORS | GID4, MDM2, XIAP | HTR2A 3413/4885HTR1A 3418/4885HTR6 2736/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.