Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CCR4 | P51679 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271236 | 0.93 | P2RX7 (0.40) | PTGDR2MRGPRX4SLC22A12GAAACLY | |
| SCHEMBL272250 | 0.92 | RORC (0.41) | PTGDR2MRGPRX4KMT2ACCR4GAA | |
| SCHEMBL271411 | 0.87 | GRM4 (0.43) | PTGDR2SLC22A12HDAC6KMT2AGAA | |
| SCHEMBL269850 | 0.86 | NOTUM (0.39) | PTGDR2MRGPRX4L3MBTL1CCR4 | |
| SCHEMBL271510 | 0.86 | P2RX7 (0.41) | MRGPRX4CCR4NR1H2 | |
| SCHEMBL271872 | 0.83 | SCD (0.42) | L3MBTL1KMT2ACCR4GAA | |
| SCHEMBL271264 | 0.83 | L3MBTL1 (0.37) | L3MBTL1KMT2AMEN1GAAACLY | |
| SCHEMBL271302 | 0.82 | MAOB (0.45) | MRGPRX4L3MBTL1KMT2AMEN1GAA | |
| SCHEMBL271821 | 0.82 | NOTUM (0.39) | PTGDR2MRGPRX4L3MBTL1GAAMAPT | |
| SCHEMBL270825 | 0.80 | POLQ (0.41) | PTGDR2KMT2AMEN1CFTRACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220056-B1 | HERBICIDAL COMPOUNDS | SYNGENTA LTD (GB) | 2015-09-30 | — | — | EP | disclosed |
| US-8133849-B2 | Herbicidal compounds | SYNGENTA LIMITED (GB) | 2012-03-13 | — | — | US | disclosed |
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-23 | — | — | US | disclosed |
| EP-2220056-A1 | HERBICIDAL COMPOUNDS | Syngenta Limited (GB) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009063180-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100323889-A1 | HERBICIDAL COMPOUNDS | CBR3, DDT, CBR1 | PTGDR2 2356/4885MRGPRX4 1864/4885SLC22A12 2545/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.