Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 4/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.36 |
| ▸ | MMP1 | P03956 | 2/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27207157 | 1.00 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2ASMN1; SMN2TAS2R14 | |
| SCHEMBL30689711 | 0.84 | ALDH1A1 (0.36) | ALDH1A1MEN1KMT2ASMN1; SMN2TAS2R14 | |
| SCHEMBL27201966 | 0.83 | TAS2R14 (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2TAS2R14 | |
| SCHEMBL27201854 | 0.81 | GLA (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2TAS2R14 | |
| SCHEMBL27207282 | 0.81 | GLA (0.39) | ALDH1A1MEN1KMT2ASMN1; SMN2TAS2R14 | |
| SCHEMBL14062319 | 0.70 | ACHE (0.49) | ALDH1A1MEN1KMT2ASMN1; SMN2GLA | |
| SCHEMBL30865701 | 0.69 | JAK2 (0.35) | MEN1KMT2ATAS2R14GLAKDM1A | |
| SCHEMBL31404011 | 0.68 | GLA (0.51) | ALDH1A1MEN1KMT2ATAS2R14GLA | |
| SCHEMBL30689733 | 0.67 | NR1D1 (0.35) | MEN1KMT2ATAS2R14GLAKDM1A | |
| SCHEMBL27201984 | 0.67 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2POLBTSHRMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132525-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2024-04-25 | — | — | US | disclosed |
| WO-2023244775-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | Boehringer Ingelheim Animal Health USA Inc. (US) | 2023-12-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132525-A1 | BORON CONTAINING PYRIMIDINE COMPOUNDS, COMPOSITIONS COMPRISING THEM, METHODS AND USES THEREOF | JAK2, JAK1, JAK3 | ALDH1A1 3629/4885MEN1 2028/4885KMT2A 1391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.