Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 5/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 5/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29793288 | 0.81 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2HPGDMTNR1A | |
| SCHEMBL29080227 | 0.76 | ALDH1A1 (0.43) | NPC1RAB9ASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL27202053 | 0.72 | BCL2 (0.42) | BCL2BCL2L1MCL1ALDH1A1GAA | |
| SCHEMBL27202085 | 0.72 | BCL2L1 (0.59) | BCL2BCL2L1MCL1MEN1KMT2A | |
| SCHEMBL28698421 | 0.70 | HTR6 (0.50) | SMN1; SMN2HPGDRECQLALDH1A1CYP3A4 | |
| SCHEMBL3661739 | 0.69 | CA2 (0.56) | NPC1RAB9ASMN1; SMN2MTNR1AMTNR1B | |
| SCHEMBL30309077 | 0.67 | BCAT2 (0.59) | NPC1RAB9ASMN1; SMN2SIRT1RECQL | |
| SCHEMBL10383424 | 0.66 | KDM4E (0.34) | NPC1RAB9ASMN1; SMN2HPGDSIRT1 | |
| SCHEMBL26858769 | 0.65 | BCL2L1 (0.48) | BCL2BCL2L1MCL1ALDH1A1GAA | |
| SCHEMBL4730471 | 0.64 | CA2 (0.59) | ALDH1A1GAALMNACYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-04-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132431-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | MGMT, MCL1, FANCF | NPC1 4062/4885RAB9A 2634/4885SMN1; SMN2 3318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.