Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468700 | 0.81 | LOXL2 (0.49) | NPC1RAB9AMAPTLOXL2TP53 | |
| SCHEMBL5703678 | 0.77 | HDAC3 (0.50) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| SCHEMBL6630971 | 0.77 | HDAC3 (0.47) | NPC1RAB9AMAPTLOXL2TP53 | |
| SCHEMBL6207598 | 0.77 | HDAC3 (0.50) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| SCHEMBL24928637 | 0.76 | LOXL2 (0.47) | NPC1RAB9AMAPTLOXL2TP53 | |
| Hydrochloric Acid SCHEMBL3621160 | 0.76 | LOXL2 (0.47) | NPC1RAB9AMAPTLOXL2TP53 | |
| Hydrochloric Acid SCHEMBL7255759 | 0.75 | HDAC3 (0.49) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7255756 | 0.75 | HDAC3 (0.49) | NPC1RAB9AMAPTLOXL2SMN1; SMN2 | |
| SCHEMBL14562892 | 0.75 | HSF1 (0.44) | NPC1RAB9AMAPTLOXL2TP53 | |
| SCHEMBL6206770 | 0.74 | MAPT (0.48) | NPC1RAB9AMAPTTP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11981645-B1 | N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as antimicrobial compound | King Faisal University (SA) | 2024-05-14 | — | — | US | claimed |
| US-11981645-B1 | N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as antimicrobial compound | King Faisal University (SA) | 2024-05-14 | — | — | US | disclosed |
| US-11970467-B1 | N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as an antimicrobial compound | King Faisal University (SA) | 2024-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11981645-B1 | N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as antimicrobial compound | NOC2L, NIT2, NAALAD2 | NPC1 1347/4885RAB9A 3369/4885MAPT 3151/4885 |
| US-11970467-B1 | N′-(2-naphthoyloxy)-2-(benzo[d]oxazol-2-yl)acetimidamide as an antimicrobial compound | NOC2L, NIT2, NAAA | NPC1 1073/4885RAB9A 3421/4885MAPT 3331/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.