Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | OGG1 | O15527 | 1/20 | 0.44 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666781 | 0.85 | MCL1 (0.58) | MCL1HDAC1HDAC8HDAC6LMNA | |
| SCHEMBL27629193 | 0.81 | MCL1 (0.53) | MCL1HDAC1HDAC8HDAC6LMNA | |
| SCHEMBL3192118 | 0.79 | LMNA (0.69) | MCL1HDAC1HDAC8HDAC6LMNA | |
| SCHEMBL15700018 | 0.75 | LMNA (0.41) | MCL1HDAC1HDAC8HDAC6LMNA | |
| SCHEMBL64428 | 0.73 | MCL1 (0.73) | MCL1HDAC1HDAC8HDAC6LMNA | |
| SCHEMBL30368759 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4EALOX15 | |
| SCHEMBL11674250 | 0.71 | ALDH1A1 (0.52) | ALDH1A1KDM4EALOX15 | |
| SCHEMBL28540289 | 0.71 | GPR3 (0.50) | MCL1HDAC1HDAC8HDAC6LMNA | |
| SCHEMBL28322189 | 0.70 | LOXL2 (0.57) | MCL1HDAC1HDAC8HDAC6LMNA | |
| SCHEMBL15557963 | 0.69 | ALDH1A1 (0.50) | MCL1LMNAALDH1A1KDM4ERAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2635559-A2 | NEUROTRYPSIN INHIBITORS | Neurotune AG (CH) | 2013-09-11 | — | — | EP | disclosed |
| WO-2012059442-A2 | NEUROTRYPSIN INHIBITORS | NEUROTUNE AG (CH) | 2012-05-10 | — | — | WO | disclosed |