Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722462 | 0.94 | POLB (0.44) | ABCB1CA1CA2POLBMAPT | |
| SCHEMBL2723562 | 0.87 | DRD2 (0.50) | ABCB1CA1CA2POLBMAPT | |
| SCHEMBL2724010 | 0.83 | KDM4E (0.50) | ABCB1MAPTDRD3ALDH1A1DRD2 | |
| SCHEMBL2722406 | 0.81 | CASP3 (0.40) | HTR7CA1CA2POLBMAPT | |
| SCHEMBL2723930 | 0.81 | CASP3 (0.40) | CA1CA2POLBMAPTLMNA | |
| Hydrochloric Acid SCHEMBL2723178 | 0.80 | CASP3 (0.39) | CA1CA2POLBMAPTALDH1A1 | |
| SCHEMBL2721650 | 0.80 | DRD4 (0.42) | HTR7MAPTLMNAALDH1A1DRD4 | |
| SCHEMBL2724597 | 0.79 | PKM (0.42) | CA1CA2POLBMAPTLMNA | |
| SCHEMBL2721489 | 0.78 | CASP3 (0.41) | CA1CA2POLBMAPTLMNA | |
| SCHEMBL2724478 | 0.76 | LMNA (0.42) | CA1CA2MAPTLMNADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054332-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |