Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | FNTA | P49354 | 9/20 | 0.49 |
| ▸ | FNTB | P49356 | 9/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27211444 | 0.88 | ALDH1A1 (0.51) | BCHEACHEALDH1A1FNTAFNTB | |
| SCHEMBL27211499 | 0.88 | FNTA (0.52) | ALDH1A1FNTAFNTBMAPTGAA | |
| SCHEMBL27211517 | 0.88 | FNTA (0.52) | BCHEACHEALDH1A1FNTAFNTB | |
| SCHEMBL27211468 | 0.75 | ALDH1A1 (0.47) | ALDH1A1FNTAFNTBMAPTKMT2A | |
| SCHEMBL24748998 | 0.75 | KLF10 (0.41) | BCHEACHEALDH1A1FNTAFNTB | |
| SCHEMBL29766498 | 0.74 | ALDH1A1 (0.56) | ACHEALDH1A1FNTAFNTBMEN1 | |
| SCHEMBL26830001 | 0.73 | ALDH1A1 (0.54) | BCHEACHEALDH1A1FNTAFNTB | |
| SCHEMBL26413682 | 0.72 | FNTA (0.59) | ALDH1A1FNTAFNTBGAAKDM4E | |
| SCHEMBL26131444 | 0.72 | FNTA (0.62) | ALDH1A1FNTAFNTBMEN1KMT2A | |
| SCHEMBL26829994 | 0.72 | ALDH1A1 (0.52) | BCHEACHEALDH1A1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11976066-B1 | Substituted 7-amino-3-(substituted benzoyl)indolizine-1-carboxylates as anti-tubercular agents | King Faisal University (SA) | 2024-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11976066-B1 | Substituted 7-amino-3-(substituted benzoyl)indolizine-1-carboxylates as anti-tubercular agents | BET1, INMT, IDO1 | BCHE 806/4885ACHE 1939/4885ALDH1A1 612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.