SCHEMBL27214742

SCHEMBL27214742

CN(C(=O)c1ccc(N)cc1)C(=O)C1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.53

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 15/20 0.53
KMT2A Q03164 2/20 0.50
USP30 Q70CQ3 1/20 0.49
MEN1 O00255 1/20 0.48
PTPN2 P17706 1/20 0.48
PTPN1 P18031 1/20 0.48
PTPN6 P29350 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27214747 0.84 ALDH1A1 (0.56) GPR119KMT2AUSP30PTPN2PTPN1
SCHEMBL24833605 0.83 MGLL (0.56) GPR119KMT2APTPN2PTPN1PTPN6
SCHEMBL21088061 0.81 KMT2A (0.54) GPR119KMT2APTPN2PTPN1PTPN6
SCHEMBL20057626 0.78 GPR119 (0.83) GPR119
SCHEMBL12426680 0.76 HDAC4 (0.61) GPR119KMT2AUSP30MEN1
SCHEMBL27178814 0.76 PDK2 (0.54) GPR119KMT2AUSP30MEN1PTPN2
SCHEMBL14113582 0.75 GPR119 (0.55) GPR119KMT2A
SCHEMBL1087013 0.75 HPGD (0.60) GPR119KMT2APTPN2PTPN1PTPN6
SCHEMBL270733 0.75 NAMPT (0.60) GPR119PTPN2PTPN1PTPN6
SCHEMBL2849980 0.75 KMT2A (0.54) GPR119KMT2AMEN1PTPN2PTPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594319-A1 BICYCLIC COMPOUNDS Aligos Therapeutics, Inc. (US) 2025-08-06 EP disclosed
US-20240150351-A1 BICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. 2024-05-09 US disclosed
WO-2024073559-A1 BICYCLIC COMPOUNDS ALIGOS THERAPEUTICS, INC. (US) 2024-04-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240150351-A1 BICYCLIC COMPOUNDS SLC10A1, PKD1, CYP11B2 GPR119 855/4885KMT2A 3870/4885USP30 4543/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.