SCHEMBL27214768

SCHEMBL27214768

Cc1ccc(N)n1CC(=O)c1ccc(Cl)cc1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.51
CXCR3 P49682 10/20 0.51
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
MAPT P10636 3/20 0.47
LMNA P02545 1/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CLK2 P49760 1/20 0.45
DYRK1A Q13627 1/20 0.45
CLK4 Q9HAZ1 1/20 0.45
IDO1 P14902 2/20 0.45
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
GSK3B P49841 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7214228 0.69 GSK3B (0.64) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL17187853 0.69 GSK3B (0.64) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL196299 0.69 GSK3B (0.64) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL12220178 0.68 GSK3B (0.52) RAB9ACXCR3MEN1KMT2AMAPT
SCHEMBL14373587 0.68 CXCR3 (1.00) RAB9ACXCR3MEN1KMT2AMAPT
SCHEMBL11530650 0.68 KDR (0.53) RAB9ACXCR3MEN1KMT2AMAPT
SCHEMBL15340905 0.67 KMT2A (0.64) RAB9AMEN1KMT2AMAPTLMNA
Bromide SCHEMBL2532767 0.67 RAB9A (0.51) RAB9ACXCR3MEN1KMT2AMAPT
SCHEMBL318783 0.66 HSD17B3 (0.67) RAB9AMEN1KMT2AMAPTLMNA
SCHEMBL10551432 0.66 ALDH1A1 (0.58) RAB9AMEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240151993-A1 ELECTRON WITHDRAWING GROUP (EWG)-CONTAINING ORGANIC MOLECULES FOR IMPROVED OPTICAL PROPERTIES IN AR/VR COMPONENTS META PLATFORMS TECHNOLOGIES, LLC 2024-05-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240151993-A1 ELECTRON WITHDRAWING GROUP (EWG)-CONTAINING ORGANIC MOLECULES FOR IMPROVED OPTICAL PROPERTIES IN AR/VR COMPONENTS AR, OR10J3, ESRRG RAB9A 2182/4885CXCR3 1345/4885MEN1 4718/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.