SCHEMBL27217482

SCHEMBL27217482

Brc1ccc(C23CC4CC(CC(C4)C2)C3)c(I)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
RAD52 P43351 1/20 0.39
POLB P06746 2/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
ALDH1A1 P00352 4/20 0.35
LMNA P02545 2/20 0.35
P2RX7 Q99572 1/20 0.33
KDM1A O60341 1/20 0.33
P2RX4 Q99571 1/20 0.33
MAPT P10636 3/20 0.33
THRB P10828 2/20 0.33
USP2 O75604 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
HDAC3 O15379 1/20 0.32
HDAC4 P56524 1/20 0.32
HDAC7 Q8WUI4 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC11 Q96DB2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26272370 0.79 MEN1 (0.36) MEN1KMT2ARAD52POLBGAA
SCHEMBL6033366 0.79 MEN1 (0.47) MEN1KMT2ARAD52POLBGAA
SCHEMBL178123 0.75 MEN1 (0.51) MEN1KMT2APOLBGAAGFER
SCHEMBL12257921 0.75 KDM1A (0.37) MEN1KMT2ARAD52POLBGAA
SCHEMBL3309247 0.75 HDAC11 (0.43) MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL27650736 0.74 TDP1 (0.42) MEN1KMT2ARAD52POLBGAA
SCHEMBL28174689 0.73 SIGMAR1 (0.41) MEN1KMT2APOLBGAAGFER
SCHEMBL2709413 0.72 LMNA (0.63) MEN1KMT2ARAD52POLBGAA
SCHEMBL25709691 0.72 LMNA (0.63) MEN1KMT2ARAD52POLBGAA
SCHEMBL25709655 0.72 LMNA (0.63) MEN1KMT2ARAD52POLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240164208-A1 ORGANIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2024-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240164208-A1 ORGANIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME OR10J3, LEF1, L1CAM MEN1 1358/4885KMT2A 1780/4885RAD52 2898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.