Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 13/20 | 0.63 |
| ▸ | TNKS | O95271 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.63 |
| ▸ | AXIN2 | Q9Y2T1 | 3/20 | 0.63 |
| ▸ | MAPT | P10636 | 7/20 | 0.60 |
| ▸ | THRB | P10828 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 7/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | SULT2A1 | Q06520 | 1/20 | 0.54 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16447499 | 0.78 | TNKS2 (1.00) | TNKS2TNKSCYP3A4CYP2C9AXIN2 | |
| SCHEMBL11919921 | 0.72 | TNKS2 (0.76) | TNKS2TNKSCYP3A4CYP2C9AXIN2 | |
| SCHEMBL11919898 | 0.70 | TNKS2 (1.00) | TNKS2TNKSCYP3A4CYP2C9AXIN2 | |
| SCHEMBL14788168 | 0.69 | SIRT2 (0.74) | MAPTTHRBSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11919903 | 0.69 | TP53 (1.00) | TNKS2TNKSCYP3A4CYP2C9AXIN2 | |
| SCHEMBL11919906 | 0.69 | TP53 (0.82) | TNKS2TNKSCYP3A4CYP2C9AXIN2 | |
| SCHEMBL27218866 | 0.68 | MAPT (0.58) | TNKS2TNKSCYP3A4CYP2C9AXIN2 | |
| SCHEMBL16010756 | 0.68 | TNKS2 (1.00) | TNKS2TNKSCYP3A4CYP2C9AXIN2 | |
| SCHEMBL17513948 | 0.67 | SIRT2 (0.65) | MAPTTHRBSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL1220782 | 0.67 | SMN1; SMN2 (0.66) | MAPTTHRBSMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4232448-B1 | AGONISTS OF FREE FATTY ACID RECEPTOR 1 AND THEIR USE IN DISEASES ASSOCIATED WITH SAID RECEPTOR | Halo Therapeutics Ltd (GB) | 2025-05-07 | — | — | EP | disclosed |
| EP-3956323-B1 | OXAZOLE AND OXADIAZOLE DERIVATIVES USEFUL AS AGONISTS OF FREE FATTY ACID RECEPTOR 1 | Halo Therapeutics Ltd (GB) | 2025-03-05 | — | — | EP | disclosed |
| US-20240158382-A1 | Agonists Of Free Fatty Acid Receptor 1 And Their Use In Diseases Associated With Said Receptor | Halo Therapeutics Ltd (GB) | 2024-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240158382-A1 | Agonists Of Free Fatty Acid Receptor 1 And Their Use In Diseases Associated With Said Receptor | FFAR1, FFAR2, FFAR3 | TNKS2 4042/4885TNKS 4259/4885CYP3A4 2824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.