Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 10/20 | 0.68 |
| ▸ | CTSL | P07711 | 1/20 | 0.62 |
| ▸ | CTSB | P07858 | 1/20 | 0.62 |
| ▸ | CTSS | P25774 | 1/20 | 0.62 |
| ▸ | CTSK | P43235 | 1/20 | 0.62 |
| ▸ | MERTK | Q12866 | 5/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | GSK3A | P49840 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224044 | 0.83 | MERTK (0.81) | MERTKKMT2AMEN1GSK3AGSK3B | |
| SCHEMBL30896201 | 0.82 | MERTK (0.65) | CTSLCTSSCTSKMERTKNPY5R | |
| SCHEMBL27223511 | 0.82 | MERTK (0.75) | ABCG2MERTKKMT2AMEN1NPY5R | |
| SCHEMBL30896246 | 0.82 | MERTK (0.65) | ABCG2MERTKNPY5RPDE5A | |
| SCHEMBL27224015 | 0.82 | MERTK (0.65) | ABCG2MERTKNPY5RPDE5A | |
| SCHEMBL27223336 | 0.82 | MERTK (0.65) | CTSLCTSSCTSKMERTKNPY5R | |
| SCHEMBL14256629 | 0.80 | ABCG2 (0.98) | ABCG2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL27224013 | 0.80 | PDE5A (0.64) | MERTKNPY5RPDE5A | |
| SCHEMBL24649757 | 0.79 | MERTK (0.64) | ABCG2MERTKNPY5RPOLB | |
| SCHEMBL30896191 | 0.79 | MERTK (0.64) | ABCG2MERTKNPY5RPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | UNIV JEFFERSON (US) | 2024-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | ADRB2, ADRB1, ADRB3 | ABCG2 1632/4885CTSL 2632/4885CTSB 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.