Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 7/20 | 0.64 |
| ▸ | MERTK | Q12866 | 6/20 | 0.59 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.51 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224044 | 0.83 | MERTK (0.81) | PDE5AMERTKNPY5R | |
| SCHEMBL27223511 | 0.82 | MERTK (0.75) | PDE5AMERTKNPY5R | |
| SCHEMBL27224015 | 0.82 | MERTK (0.65) | PDE5AMERTKNPY5RCAMK2D | |
| SCHEMBL30896201 | 0.82 | MERTK (0.65) | PDE5AMERTKNPY5RCAMK2D | |
| SCHEMBL30896246 | 0.82 | MERTK (0.65) | PDE5AMERTKNPY5RCAMK2D | |
| SCHEMBL27223336 | 0.82 | MERTK (0.65) | PDE5AMERTKNPY5RCAMK2D | |
| SCHEMBL27223333 | 0.80 | ABCG2 (0.68) | PDE5AMERTKNPY5R | |
| SCHEMBL24649757 | 0.79 | MERTK (0.64) | MERTKNPY5RCAMK2D | |
| SCHEMBL30896191 | 0.79 | MERTK (0.64) | MERTKNPY5RCAMK2D | |
| SCHEMBL14256561 | 0.79 | MERTK (0.67) | PDE5AMERTKNPY5RCAMK2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | UNIV JEFFERSON (US) | 2024-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166626-A1 | Compounds and Methods for Preventing, Treating, or Ameliorating Airway Disease | ADRB2, ADRB1, ADRB3 | PDE5A 285/4885MERTK 3423/4885NPY5R 2011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.