SCHEMBL272276

SCHEMBL272276

Nc1cc(C(F)(c2ccc(O)c(N)c2)C(F)(F)C(F)(F)F)ccc1O

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.55
GAA P10253 7/20 0.55
MAPT P10636 4/20 0.55
MEN1 O00255 3/20 0.55
KMT2A Q03164 3/20 0.55
PKM P14618 3/20 0.55
RECQL P46063 2/20 0.55
CHEK1 O14757 1/20 0.41
FYN P06241 1/20 0.41
PDGFRB P09619 1/20 0.41
PIM1 P11309 1/20 0.41
FGFR1 P11362 1/20 0.41
FLT1 P17948 1/20 0.41
GRK5 P34947 1/20 0.41
MAP2K2 P36507 1/20 0.41
MAPK8 P45983 1/20 0.41
CDK8 P49336 1/20 0.41
RPS6KA3 P51812 1/20 0.41
PRKX P51817 1/20 0.41
JAK3 P52333 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28284950 0.87 HSD17B1 (0.44) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL11516602 0.85 ALDH1A1 (0.55) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL272332 0.85 HSD17B10 (0.43) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL28336803 0.82 MAPT (0.44) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL20920802 0.82 ALDH1A1 (0.38) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL29185435 0.82 ALDH1A1 (0.50) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL1025773 0.80 ALDH1A1 (0.59) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL26579 0.80 ALDH1A1 (0.59) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL31328380 0.80 ALDH1A1 (0.59) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL6757920 0.80 ALDH1A1 (0.59) ALDH1A1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 718 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112180684-B Positive photosensitive resin composition, cured film and pattern processing method thereof 武汉柔显科技股份有限公司 2024-10-11 CN claimed
CN-118108661-B Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof 波米科技有限公司 2024-09-20 CN claimed
CN-117855669-B High noise reduction type PET composite material for computer battery and preparation method thereof 惠州市冠宝新材料有限公司 2024-06-04 CN claimed
CN-118108661-A Diamine monomer with nitrogen heterocycle and benzocyclobutene structure, and preparation method and application thereof 波米科技有限公司 2024-05-31 CN claimed
CN-117855669-A High noise reduction type PET composite material for computer battery and preparation method thereof 惠州市冠宝新材料有限公司 2024-04-09 CN claimed
CN-114805094-B Preparation method of bis (3-amino-4-hydroxyphenyl) hexafluoropropane 上海如鲲新材料股份有限公司 2024-04-02 CN claimed
CN-114524938-B Polymer, photosensitive resin composition, cured film prepared from polymer and photosensitive resin composition, and electronic element 江苏三月科技股份有限公司 2024-02-09 CN claimed
CN-114672021-B High-temperature-resistant waterproof polyimide material and preparation method thereof 苏州瀚海新材料有限公司 2024-02-06 CN claimed
CN-114316591-B Dimensionally stable low-dielectric polyimide film and preparation method and application thereof 浙江中科玖源新材料有限公司 2023-09-12 CN claimed
CN-113501989-B Transparent polyimide composite conductive film 浙江中科玖源新材料有限公司 2023-04-07 CN claimed
CN-106117554-B A kind of siliceous epoxy acid imide matrix resin of BDADDS type and preparation method thereof 东华大学 2019-02-26 CN claimed
CN-109181622-A A kind of highly heat-resistant polyimide insulating materials of low-temperature setting 浙江福斯特新材料研究院有限公司 2019-01-11 CN claimed
CN-109134858-A A kind of transparent polyimide film and preparation method thereof 深圳瑞华泰薄膜科技有限公司 2019-01-04 CN claimed
CN-105367810-B A kind of preparation method and application of hexafluoropropane base PMO films 中国科学院深圳先进技术研究院 2018-07-24 CN claimed
CN-105086424-B A kind of high temperature resistant BAHPFP type copper coated foil plates and preparation method thereof 东华大学 2018-06-22 CN claimed
CN-105960682-A Thermally conductive electronic substrates and methods relating thereto E.I.内穆尔杜邦公司 2016-09-21 CN claimed
EP-1326138-B1 NEGATIVE PHOTOSENSITIVE POLYIMIDE COMPOSITION AND METHOD OF FORMING IMAGE FROM THE SAME PI R & D CO LTD (JP) 2014-11-05 EP claimed
US-8449978-B2 Insulated wire and insulating varnish used therefor HITACHI CABLE, LTD. (JP) 2013-05-28 US claimed
US-7648815-B2 Solvent solubility; adhesive; heat resistance; dielectric film pattern PI R&D CO., LTD. (JP) 2010-01-19 US claimed
WO-2009113747-A1 PREPARATION METHOD OF POLYBENZOXAZOLES BY THERMAL REARRANGEMENT, POLYBENZOXAZOLES PREPARED THEREBY, AND GAS SEPARATION MEMBRANE COMPRISING THE SAME INDUSTRY-UNIVERSITY COOPERATION FOUNDATION, HANYANG UNIVERSITY (KR) 2009-09-17 WO claimed