SCHEMBL272332

SCHEMBL272332

Nc1ccc(C(F)(c2ccc(N)c(O)c2)C(F)(F)C(F)(F)F)cc1O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.43
ALOX15 P16050 3/20 0.43
CYP3A4 P08684 1/20 0.43
MEN1 O00255 2/20 0.39
GAA P10253 2/20 0.39
MAPT P10636 2/20 0.39
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 2/20 0.39
POLB P06746 1/20 0.39
RAB9A P51151 1/20 0.39
ALDH1A1 P00352 4/20 0.37
PKM P14618 2/20 0.37
RECQL P46063 1/20 0.37
ESR1 P03372 3/20 0.35
ESR2 Q92731 2/20 0.35
AR P10275 1/20 0.35
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272276 0.85 ALDH1A1 (0.55) HSD17B10ALOX15MEN1GAAMAPT
SCHEMBL28336815 0.82 MMP2 (0.40) HSD17B10ALOX15CYP3A4MEN1GAA
SCHEMBL29185435 0.82 ALDH1A1 (0.50) HSD17B10ALOX15MEN1GAAMAPT
SCHEMBL20920802 0.82 ALDH1A1 (0.38) HSD17B10ALOX15CYP3A4MEN1GAA
SCHEMBL5958751 0.80 HSD17B10 (0.46) HSD17B10ALOX15CYP3A4MEN1GAA
SCHEMBL29399630 0.80 ESR1 (0.50) HSD17B10ALOX15CYP3A4MEN1GAA
SCHEMBL29412586 0.80 ESR1 (0.50) HSD17B10ALOX15CYP3A4MEN1GAA
SCHEMBL766058 0.80 ESR1 (0.50) HSD17B10ALOX15CYP3A4MEN1GAA
SCHEMBL3947426 0.79 HSD17B10 (0.50) HSD17B10ALOX15CYP3A4MEN1GAA
SCHEMBL1025296 0.79 ALDH1A1 (0.50) HSD17B10ALOX15CYP3A4MEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8449978-B2 Insulated wire and insulating varnish used therefor HITACHI CABLE, LTD. (JP) 2013-05-28 US claimed
US-12547074-B2 Photosensitive resin composition, method for producing patterned cured film, patterned cured film and semiconductor element RESONAC CORPORATION (JP) 2026-02-10 US disclosed
US-12405198-B2 Photosensitive resin composition, method for selecting photosensitive resin composition, method for producing patterned cured film, and method for producing semiconductor device RESONAC CORPORATION (JP) 2025-09-02 US disclosed
WO-2025128333-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
WO-2025128334-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
WO-2025128332-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MATERIALS U.S.A., INC. (US) 2025-06-19 WO disclosed
US-20250189892-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 US disclosed
US-20250188311-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 US disclosed
US-20250188312-A1 POLY-O-HYDROXYAMIDES COMPRISING NOVEL INDANE BIS-O-AMINOPHENOLS, PHOTOSENSITIVE COMPOSITIONS, DIELECTRIC FILMS, AND BUFFER COATINGS CONTAINING THE SAME FUJIFILM ELECTRONIC MAT USA INC (US) 2025-06-12 US disclosed
US-20240361697-A1 METHOD FOR SELECTING PHOTOSENSITIVE RESIN COMPOSITION, METHOD FOR PRODUCING PATTERNED CURED FILM, CURED FILM, SEMICONDUCTOR DEVICE, AND METHOD FOR PRODUCING SEMICONDUCTOR DEVICE RESONAC CORPORATION (JP) 2024-10-31 US disclosed
US-6524764-B1 Alkali-developable; polyamide, phenol compound and/or ester of a naphthoquinone diazide sulphonic acid TORAY INDUSTRIES, INC. (JP) 2003-02-25 US disclosed
US-20020162998-A1 Display TORAY INDUSTRIES, INC. (JP) 2002-11-07 US disclosed
US-6365306-B2 ADDING A DISSOLUTION INHIBITOR TO A POLYMER SOLUBLE IN AN AQUEOUS ALKALINE DEVELOPER AND A QUINONEDIAZIDE PHOTOSENSITIZER TO INCREASE THE SOLUBILITY DIFFERENCE BETWEEN THE EXPOSED AND UNEXPOSED PARTS; FINENESS; RESOLUTION; FILMS HITACHI CHEMICAL DUPONT MICROSYSTEMS L.L.C. 2002-04-02 US disclosed
US-6340546-B1 WHICH, ON HEATING, BECOME HEAT-RESISTANT POLYIMIDE POLYMERS SUITABLE FOR SURFACE-PROTECTING FILMS, INTERLAYER INSULATING FILMS HITACHI CHEMICAL DUPONT MICROSYSTEMS LTD. (JP) 2002-01-22 US disclosed
EP-1132773-A1 POSITIVE-TYPE PHOTOSENSITIVE POLYIMIDE PRECURSOR COMPOSITION TORAY INDUSTRIES, INC. (JP) 2001-09-12 EP disclosed
US-20010009746-A1 Photosensitive polymer composition, method for forming relief patterns, and electronic parts NUNOMURA MASATAKA (JP) 2001-07-26 US disclosed
US-6232032-B1 MIXTURE OF POLYBENZOXAZOLE AND POLYAMIDE HITACHI CHEMICAL DUPONT MICROSYSTEMS L.L.C. 2001-05-15 US disclosed
EP-1028354-A1 Positive photosensitive resin composition, method of forming relief pattern, and electronic part Hitachi Chemical DuPont MicroSystems Ltd. (JP) 2000-08-16 EP disclosed
EP-0961169-A1 Photosensitive polymer composition, method for forming relief patterns, and electronic parts Hitachi Chemical DuPont MicroSystems Ltd. (JP) 1999-12-01 EP disclosed
EP-0863436-A1 Heat resistant photosensitive polymer composition, process for forming pattern and semiconductor device HITACHI CHEMICAL CO., LTD. (JP) 1998-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12547074-B2 Photosensitive resin composition, method for producing patterned cured film, patterned cured film and semiconductor element JMJD6, RARA, BCR HSD17B10 2940/4885ALOX15 2728/4885CYP3A4 2409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.