SCHEMBL27229448

SCHEMBL27229448

Cn1nc2cccc(B(O)O)c2c1F

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ SLC9A1 P19634 1/20 0.32
▸ KEAP1 Q14145 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27229442 0.77 — —
SCHEMBL27229417 0.75 PDPK1 (0.37) SLC9A1KEAP1
SCHEMBL28137695 0.75 AXL (0.37) SLC9A1KEAP1
SCHEMBL27229416 0.75 CHRM4 (0.30) —
SCHEMBL29303154 0.72 ELANE (0.35) SLC9A1KEAP1
SCHEMBL31439795 0.70 — —
SCHEMBL27965302 0.67 SLC9A1 (0.43) SLC9A1KEAP1
SCHEMBL29956191 0.67 MAPK13 (0.38) SLC9A1KEAP1
SCHEMBL3712944 0.66 SLC9A1 (0.38) SLC9A1KEAP1
SCHEMBL27359770 0.64 PDE10A (0.38) SLC9A1KEAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4608820-A1 HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING Boehringer Ingelheim International GmbH (DE) 2025-09-03 — — EP disclosed
CN-120077034-A Heterocyclic compounds capable of activating STING 勃林格殷格翰国际公司 2025-05-30 — — CN disclosed
US-20240174641-A1 HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) 2024-05-30 — — US disclosed
WO-2024089006-A1 HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2024-05-02 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240174641-A1 HETEROCYCLIC COMPOUNDS CAPABLE OF ACTIVATING STING STING1, CGAS, IRF3 SLC9A1 2694/4885KEAP1 69/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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