Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP2 | O95551 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29303154 | 0.75 | ELANE (0.35) | KDM4EMAPTHSD17B10ALDH1A1KMT2A | |
| SCHEMBL13733086 | 0.68 | MAPT (0.41) | MAPTPOLBKMT2ASLC9A1KEAP1 | |
| SCHEMBL31439989 | 0.67 | BACE1 (0.38) | AXLMAPTPOLBSLC9A1KEAP1 | |
| SCHEMBL8536634 | 0.65 | PARP1 (0.36) | AXLALDH1A1KMT2AMEN1HSP90AB1 | |
| SCHEMBL21653691 | 0.64 | PTPN11 (0.32) | — | |
| SCHEMBL13106207 | 0.64 | HSP90AB1 (0.39) | ALDH1A1POLBKMT2ASLC9A1KEAP1 | |
| SCHEMBL7134676 | 0.64 | MAPK13 (0.40) | AXLKDM4EMAPTALDH1A1KMT2A | |
| SCHEMBL30847906 | 0.63 | DDB1 (0.47) | KDM4EMAPTHSD17B10ALDH1A1KMT2A | |
| SCHEMBL7850281 | 0.63 | MEN1 (0.46) | ALDH1A1KMT2AMEN1HSP90AB1 | |
| SCHEMBL16993895 | 0.62 | SLC9A1 (0.48) | KDM4EMAPTHSD17B10ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106604997-A | Inhibitors of lysine specific demethylase-1 | 赛尔基因昆蒂赛尔研究公司 | 2017-04-26 | — | — | CN | disclosed |