Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ACACB | O00763 | 2/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CHKA | P35790 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722952 | 0.88 | LOXL2 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL2724388 | 0.88 | ACACB (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL1205833 | 0.86 | ACACB (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6168895 | 0.85 | CYP3A4 (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| Hydrochloric Acid SCHEMBL3095011 | 0.85 | ACACB (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL2722211 | 0.84 | IDO1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6169204 | 0.84 | ACACB (0.43) | ALDH1A1ACACBCHKACA1CA2 | |
| SCHEMBL2721804 | 0.83 | ACKR3 (0.45) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6171960 | 0.82 | MAPT (0.51) | MEN1KMT2AALDH1A1MAPTL3MBTL1 | |
| SCHEMBL2724597 | 0.81 | PKM (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054332-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |