Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2722964 | 0.88 | MEN1 (0.49) | ACACBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2724388 | 0.87 | ACACB (0.41) | LOXL2ACACBMEN1KMT2AALDH1A1 | |
| SCHEMBL2722211 | 0.84 | IDO1 (0.41) | LOXL2ACACBMEN1KMT2AALDH1A1 | |
| SCHEMBL2721804 | 0.82 | ACKR3 (0.45) | ACACBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6169204 | 0.82 | ACACB (0.43) | ACACBALDH1A1CYP3A4CA1CA2 | |
| SCHEMBL2721467 | 0.81 | PRMT5 (0.47) | MEN1KMT2AALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL6168895 | 0.79 | CYP3A4 (0.47) | ACACBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2724597 | 0.77 | PKM (0.42) | ACACBMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL2723930 | 0.77 | CASP3 (0.40) | LOXL2ACACBALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL2724116 | 0.76 | ALDH1A1 (0.40) | ACACBMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054332-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |