Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.38 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2724388 | 0.90 | ACACB (0.41) | IDO1ALDH1A1ABHD6LOXL2ACACB | |
| SCHEMBL2722964 | 0.84 | MEN1 (0.49) | OPRM1OPRD1OPRK1ALDH1A1MAPT | |
| SCHEMBL2722952 | 0.84 | LOXL2 (0.41) | IDO1ALDH1A1ABHD6LOXL2ACACB | |
| SCHEMBL2721804 | 0.79 | ACKR3 (0.45) | ALDH1A1ACACBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6169204 | 0.79 | ACACB (0.43) | ALDH1A1ACACBCYP3A4 | |
| SCHEMBL2721467 | 0.77 | PRMT5 (0.47) | ALDH1A1SMN1; SMN2MEN1KMT2AHSD17B10 | |
| SCHEMBL6168895 | 0.76 | CYP3A4 (0.47) | ALDH1A1ACACBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL10106423 | 0.75 | LOXL2 (0.64) | ALDH1A1KDM4EMAPTLOXL2MEP1B | |
| SCHEMBL2721489 | 0.75 | CASP3 (0.41) | ALDH1A1KDM4EMAPTACACBSMN1; SMN2 | |
| SCHEMBL2724597 | 0.74 | PKM (0.42) | ALDH1A1KDM4EMAPTACACBCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012054332-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-26 | — | — | WO | disclosed |