Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 4/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27207979 | 1.00 | PTPN1 (0.42) | PTPN1AAK1ITGB3ITGA2BPRMT5 | |
| SCHEMBL30987831 | 0.91 | AAK1 (0.41) | PTPN1AAK1PRMT5WDR77DGAT1 | |
| SCHEMBL17002747 | 0.83 | CTSS (0.46) | PTPN1AAK1ITGB3ITGA2BPRMT5 | |
| SCHEMBL2949460 | 0.83 | PRMT5 (0.56) | AAK1PRMT5WDR77DGAT1USP30 | |
| SCHEMBL28821999 | 0.79 | AAK1 (0.45) | PTPN1AAK1ITGB3ITGA2BPRMT5 | |
| SCHEMBL27207972 | 0.79 | PTPN1 (0.48) | PTPN1AAK1ITGB3ITGA2BACE | |
| SCHEMBL27208784 | 0.79 | PTPN1 (0.48) | PTPN1AAK1ITGB3ITGA2BACE | |
| SCHEMBL1818990 | 0.78 | ITGB3 (0.56) | PTPN1AAK1ITGB3ITGA2BACE | |
| SCHEMBL5892821 | 0.78 | ITGB3 (0.56) | PTPN1AAK1ITGB3ITGA2BACE | |
| SCHEMBL1818988 | 0.78 | ITGB3 (0.56) | PTPN1AAK1ITGB3ITGA2BACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4361159-A1 | BORONO-PHENYLALANINE DERIVATIVE | Stella Pharma Corporation (JP) | 2024-05-01 | — | — | EP | disclosed |