Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12925096 | 0.80 | GPR35 (0.37) | GPR35CXCR2ALOX5MAPT | |
| SCHEMBL12925115 | 0.76 | GPR35 (0.37) | GPR35CXCR2ALOX5MAPT | |
| SCHEMBL16683764 | 0.73 | NR5A1 (0.37) | ALDH1A1CXCR2 | |
| SCHEMBL24023361 | 0.72 | ALDH1A1 (0.58) | ALDH1A1KCNH2MAPTSMN1; SMN2 | |
| SCHEMBL27019720 | 0.72 | ALDH1A1 (0.58) | ALDH1A1KCNH2MAPTSMN1; SMN2 | |
| SCHEMBL24023174 | 0.72 | KCNH2 (0.37) | ALDH1A1KCNH2 | |
| SCHEMBL9039937 | 0.72 | ALOX5 (0.48) | GPR35ALOX5NPC1MAPTSTAT3 | |
| SCHEMBL5542542 | 0.68 | NFKB1 (0.36) | GPR35ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL17008157 | 0.67 | TSHR (0.57) | ALDH1A1KCNH2 | |
| SCHEMBL13630791 | 0.67 | ALDH1A1 (0.62) | ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2630179-B1 | CONJUGATED POLYMERS | RAYNERGY TEK INC (TW) | 2021-04-14 | — | — | EP | disclosed |
| US-9559303-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9559303-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| US-9559303-B2 | Conjugated polymers | MERCK PATENT GMBH (DE) | 2017-01-31 | — | — | US | disclosed |
| EP-2630179-A1 | CONJUGATED POLYMERS | Merck Patent GmbH (DE) | 2013-08-28 | — | — | EP | disclosed |
| US-20130214208-A1 | Conjugated Polymers | MERCK PATENT GMBH (DE) | 2013-08-22 | — | — | US | disclosed |
| US-20130214208-A1 | Conjugated Polymers | MERCK PATENT GMBH (DE) | 2013-08-22 | — | — | US | disclosed |
| US-20130214208-A1 | Conjugated Polymers | MERCK PATENT GMBH (DE) | 2013-08-22 | — | — | US | disclosed |
| WO-2012052099-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012052099-A1 | CONJUGATED POLYMERS | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |