Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.67 |
| ▸ | GFER | P55789 | 1/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | CCNK | O75909 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 1/20 | 0.51 |
| ▸ | CCND3 | P30281 | 1/20 | 0.51 |
| ▸ | CDK9 | P50750 | 1/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.51 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29330592 | 0.86 | CCND3 (0.51) | RAD52GFERMEN1KMT2AMAPT | |
| SCHEMBL27236232 | 0.85 | GAA (0.50) | RAD52GFERAPPIDEMEN1 | |
| SCHEMBL11728397 | 0.83 | RAD52 (0.69) | RAD52GFERAPPMEN1KMT2A | |
| SCHEMBL29329139 | 0.82 | RAD52 (0.78) | RAD52GFERAPPMEN1KMT2A | |
| SCHEMBL3709053 | 0.82 | IDE (0.76) | IDEMEN1KMT2AMAPTRXFP1 | |
| SCHEMBL14758370 | 0.81 | RAD52 (1.00) | RAD52GFERAPPMAPTGAA | |
| SCHEMBL1873094 | 0.81 | ALDH1A1 (0.61) | IDEMEN1KMT2AMAPTGAA | |
| SCHEMBL11812563 | 0.79 | RAD52 (0.64) | RAD52GFERAPPMEN1KMT2A | |
| SCHEMBL30993299 | 0.79 | IDE (0.51) | IDEMEN1KMT2AMAPTRXFP1 | |
| SCHEMBL16217103 | 0.79 | RAD52 (0.79) | RAD52GFERAPPKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092255-A9 | 4-AMINOQUINOLINES FOR TREATMENT OF MULTIDRUG RESISTANT MALARIA | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS (US) | 2024-07-18 | — | — | WO | disclosed |