SCHEMBL2723697

SCHEMBL2723697

NNC(=O)C1=CC=CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 2/20 0.35
MAPT P10636 4/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
MPO P05164 2/20 0.31
CYP3A4 P08684 2/20 0.31
BLM P54132 2/20 0.31
KDM5A P29375 1/20 0.31
GFER P55789 1/20 0.31
PMP22 Q01453 1/20 0.31
HIF1A Q16665 1/20 0.31
KDM4E B2RXH2 4/20 0.31
ALDH1A1 P00352 2/20 0.31
LMNA P02545 2/20 0.31
L3MBTL1 Q9Y468 2/20 0.31
NSD2 O96028 1/20 0.31
ALPL P05186 1/20 0.31
POLB P06746 1/20 0.31
ALPI P09923 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3916804 0.79 P2RX7 (0.34) P2RX7MAPTCA1CA2MPO
SCHEMBL3916283 0.78
SCHEMBL9459241 0.77
SCHEMBL9158697 0.75
SCHEMBL16102240 0.75
SCHEMBL44788 0.75 MAOA (0.32)
SCHEMBL7767135 0.74 CRHBP (0.42) MAPTCA1CA2GFERKDM4E
SCHEMBL5691370 0.74 POLB (0.44) MAPTGFERKDM4EALDH1A1LMNA
SCHEMBL5969293 0.74
SCHEMBL9699942 0.73 RAB9A (0.50) GFERKDM4EALDH1A1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12018114-B2 Polymeric material including a uretdione-containing material and a thermally activatable amine, two-part compositions, and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-06-25 US disclosed
EP-4377373-A1 CURABLE, ONE-PART, DUAL-STAGE THIOL-ENE-EPOXY LIQUID ADHESIVES AND METHODS 3M Innovative Properties Company (US) 2024-06-05 EP disclosed
US-11988304-B2 Tubular elements with adhesive joint, method of joining tubular elements thereof 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-05-21 US disclosed
US-11894164-B2 Stretchable conductors 3M INNOVATIVE PROPERTIES COMPNAY (US) 2024-02-06 US disclosed
US-11884850-B2 Adhesive film including a (meth)acrylate matrix including a curable epoxy/thiol resin composition, tape, and method 3M INNOVATIVE PROPERTIES COMPANY (US) 2024-01-30 US disclosed
EP-4001339-B1 AN EPOXY COMPOSITION COMPRISING A BIO-BASED EPOXY COMPOUND HENKEL AG & CO KGAA (DE) 2024-01-24 EP disclosed
US-20230312911-A1 EPOXY COMPOSITION COMPRISING A BIO-BASED EPOXY COMPOUND HENKEL AG & CO KGAA (DE) 2023-10-05 US disclosed
US-11584823-B2 Epoxy stabilization using substituted barbituric acids 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-02-21 US disclosed
WO-2023007439-A1 CURABLE, ONE-PART, DUAL-STAGE THIOL-ENE-EPOXY LIQUID ADHESIVES AND METHODS 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-02-02 WO disclosed
EP-4001339-A1 AN EPOXY COMPOSITION COMPRISING A BIO-BASED EPOXY COMPOUND Henkel AG & Co. KGaA (DE) 2022-05-25 EP disclosed
US-6872762-B2 Epoxy resin composition with solid organic acid LOCTITE (R&D) LIMITED (IE) 2005-03-29 US disclosed
WO-2005016987-A1 CURABLE COMPOSITIONS HAVING A REDUCED ENTHALPY OUTPUT LOCTITE (R & D ) LIMITED (IE) 2005-02-24 WO disclosed
US-20040063870-A1 Curable epoxy-based compositions LOCTITE (R&D) LTD. 2004-04-01 US disclosed
US-6653371-B1 Shelf life stability BURNS BARRY E (IE) 2003-11-25 US disclosed
EP-1047744-B1 CURABLE EPOXY-BASED COMPOSITIONS LOCTITE R & D LTD (IE) 2002-10-02 EP disclosed
EP-1047744-A1 CURABLE EPOXY-BASED COMPOSITIONS Loctite (R & D) Limited (IE) 2000-11-02 EP disclosed
WO-1999036484-A1 CURABLE EPOXY-BASED COMPOSITIONS LOCTITE (R & D) LIMITED (IE) 1999-07-22 WO disclosed
EP-0459614-B1 Method for preparing a liquid epoxy resin composition SOMAR CORP (JP) 1998-09-30 EP disclosed
US-5585421-A CURABLE MIXTURE CONTAINING LIQUID EPOXIDE, AMINE CURING AGENT, CALCINED TALC, AND RHEOLOGY AGENT; POT LIFE SOMAR CORPORATION (JP) 1996-12-17 US disclosed
EP-0459614-A2 Epoxy resin composition SOMAR CORPORATION (JP) 1991-12-04 EP disclosed