SCHEMBL2723945

SCHEMBL2723945

CC(C)CC(=O)C(=O)NCCc1ccc(O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.58
F13A1 P00488 1/20 0.58
PLAAT5 Q96KN8 5/20 0.57
PLAAT4 Q9UL19 5/20 0.57
PLAAT3 P53816 4/20 0.57
PLAAT2 Q9NWW9 4/20 0.57
ABCG2 Q9UNQ0 1/20 0.52
ESRRG P62508 4/20 0.51
GAA P10253 2/20 0.49
ESRRB O95718 2/20 0.48
TMEM97 Q5BJF2 1/20 0.47
SIGMAR1 Q99720 1/20 0.47
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2D6 P10635 2/20 0.47
CYP2C19 P33261 2/20 0.47
NPC1 O15118 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10063265 0.84 KDM4E (0.62) KDM4EF13A1ABCG2ESRRGGAA
SCHEMBL15358690 0.78 KDM4E (0.73) KDM4EF13A1PLAAT5PLAAT4PLAAT3
SCHEMBL10044100 0.77 PLAAT5 (0.72) KDM4EF13A1PLAAT5PLAAT4PLAAT3
SCHEMBL10044101 0.77 KDM4E (0.57) KDM4EF13A1PLAAT5PLAAT4PLAAT3
SCHEMBL105520 0.77 KDM4E (0.71) KDM4EF13A1PLAAT5PLAAT4PLAAT3
SCHEMBL12164125 0.77 KDM4E (0.66) KDM4EF13A1ABCG2ESRRGGAA
SCHEMBL2745221 0.76 KDM4E (0.65) KDM4EF13A1PLAAT5PLAAT4PLAAT3
SCHEMBL4949918 0.76 KDM4E (0.64) KDM4EF13A1ABCG2ESRRGGAA
SCHEMBL5060920 0.76 KDM4E (0.64) KDM4EF13A1ABCG2ESRRGGAA
SCHEMBL29655176 0.76 KDM4E (0.64) KDM4EF13A1ABCG2ESRRGGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015081390-A2 METHOD FOR CONTROLLING ANT COLONIES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2015-06-11 WO claimed
US-11767289-B2 Methods and compositions for pest control UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2023-09-26 US disclosed
US-11767289-B2 Methods and compositions for pest control UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2023-09-26 US disclosed
US-20220234997-A1 Methods and Compositions for Pest Control THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2022-07-28 US disclosed
US-9950994-B2 Methods and compositions for pest control VMI FOUNDATION (US) 2018-04-24 US disclosed
US-9950994-B2 Methods and compositions for pest control VMI FOUNDATION (US) 2018-04-24 US disclosed
US-20180009740-A1 Methods and Compositions for Pest Control THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2018-01-11 US disclosed
WO-2015081390-A2 METHOD FOR CONTROLLING ANT COLONIES KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2015-06-11 WO disclosed
US-20130289125-A1 Methods and Compositions for Pest Control THE VMI FOUNDATION 2013-10-31 US disclosed
US-20130289125-A1 Methods and Compositions for Pest Control THE VMI FOUNDATION 2013-10-31 US disclosed
WO-2012061624-A2 Methods and Compositions for Pest Control VMI FOUNDATION (US) 2012-05-10 WO disclosed
WO-2012061624-A2 Methods and Compositions for Pest Control VMI FOUNDATION (US) 2012-05-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11767289-B2 Methods and compositions for pest control TYR, GLMN, SGMS2 KDM4E 424/4885F13A1 3867/4885PLAAT5 641/4885
US-20130289125-A1 Methods and Compositions for Pest Control TYR, GLMN, SGMS2 KDM4E 424/4885F13A1 3867/4885PLAAT5 641/4885
US-20180009740-A1 Methods and Compositions for Pest Control TYR, GLMN, SGMS2 KDM4E 424/4885F13A1 3867/4885PLAAT5 641/4885
US-20220234997-A1 Methods and Compositions for Pest Control TYR, GLMN, SGMS2 KDM4E 424/4885F13A1 3867/4885PLAAT5 641/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.