Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Catechol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 2/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Catechol SCHEMBL2707627 | 0.87 | CA2 (0.62) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| Catechol SCHEMBL8411371 | 0.87 | CA2 (0.62) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| Phenol SCHEMBL27435926 | 0.86 | TDP1 (0.52) | MAPTHSD17B10TSHRCA12CA2 | |
| Catechol SCHEMBL27612050 | 0.85 | MAPT (0.59) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| Catechol SCHEMBL27477125 | 0.85 | CA2 (0.59) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| Naphthalene SCHEMBL27610274 | 0.83 | NQO2 (0.46) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| Biphenyl SCHEMBL2256875 | 0.83 | NQO2 (0.55) | MAPTALDH1A1HSD17B10TSHRBLM | |
| Catechol SCHEMBL3376196 | 0.82 | HPGD (0.62) | MAPTKDM4EALDH1A1HPGDHSD17B10 | |
| Benzene SCHEMBL27293893 | 0.82 | FFAR3 (0.50) | MAPTALDH1A1HSD17B10TSHRBLM | |
| Naphthalene SCHEMBL28830071 | 0.81 | NQO2 (0.44) | MAPTKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240191108-A1 | TWO COMPONENT (2K) CURABLE ADHESIVE COMPOSITION | HENKEL AG & CO KGAA (DE) | 2024-06-13 | — | — | US | claimed |
| CN-103429528-A | Preventing or reducing scale in wet-process phosphoric acid production | CYTEC TECH CORP | 2013-12-04 | — | — | CN | claimed |
| CN-1444591-A | Method for producing chromium (III) -containing organic complexes and their use as corrosion inhibitors and corrosion-resistant coatings | COULEURS ZINCIQUES SOC NOUV (FR) | 2003-09-24 | — | — | CN | claimed |
| US-20240191108-A1 | TWO COMPONENT (2K) CURABLE ADHESIVE COMPOSITION | HENKEL AG & CO KGAA (DE) | 2024-06-13 | — | — | US | disclosed |
| CN-107541030-A | The antistatic poly-lactic acid material of bioerodible and its products formed | 汉达精密电子(昆山)有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-102858916-B | The benzotropolone and/or the relevant benzotropolone derivatives that contain plant extracts by use are stablized family expenses, watch box and food product | BASF SE (DE) | 2016-05-11 | — | — | CN | disclosed |
| CN-104204125-A | Method and apparatus for adhesive bonding in aqueous media | ZHAO BOXIN | 2014-12-10 | — | — | CN | disclosed |
| CN-104168896-A | Fixed dose combination therapy of parkinson's disease | PHARMA TWO B LTD | 2014-11-26 | — | — | CN | disclosed |
| CN-102015674-B | Modulators of dopamine neurotransmission | NSAB FILIAL AF NEUROSEARCH SWEDEN AB SVERIGE (DK) | 2014-10-29 | — | — | CN | disclosed |
| CN-102123763-B | Prodrugs of methyl hydrogen fumarate, pharmaceutical compositions thereof, and methods of use thereof | XENOPORT, INC. (US) | 2014-10-08 | — | — | CN | disclosed |
| CN-103987698-A | 2-Phenylaminopyrimidine derivatives as kinase LRRK2 modulators for the treatment of Parkinson's disease | HOFFMANN LA ROCHE | 2014-08-13 | — | — | CN | disclosed |
| CN-1816328-A | Therapeutic agent | TAKARA BIO INC (JP) | 2006-08-09 | — | — | CN | disclosed |
| CN-1249059-C | novel piperidine carboxylic acid amide derivatives, process for their preparation and pharmaceutical compositions containing them | SANOFI SYNTHELABO (FR) | 2006-04-05 | — | — | CN | disclosed |
| CN-1671373-A | Compounds for inhibiting ALDH | ENDOWMENT FOR RES IN HUMAN BIO (US) | 2005-09-21 | — | — | CN | disclosed |
| CN-1549809-A | Dithiazole compounds, matrix metalloprotease inhibitors and external preparations for the skin | ������������ʽ���� | 2004-11-24 | — | — | CN | disclosed |
| CN-1518549-A | Novel piperidinecarboxamide derivatives, method for preparing same and pharmaceutical compositions containing same | ʥŵ��-�ϳ�ʵ���ҹ�˾ | 2004-08-04 | — | — | CN | disclosed |
| CN-1489581-A | Quinazolinone derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-04-14 | — | — | CN | disclosed |
| CN-1444591-A | Method for producing chromium (III) -containing organic complexes and their use as corrosion inhibitors and corrosion-resistant coatings | COULEURS ZINCIQUES SOC NOUV (FR) | 2003-09-24 | — | — | CN | disclosed |
| CN-1419448-A | Remedies | TAKARA BIO INC (JP) | 2003-05-21 | — | — | CN | disclosed |
| CN-1076690-A | SULFONAMIDOCARBOXAMIDES | HOFFMANN LA ROCHE (CH) | 1993-09-29 | — | — | CN | disclosed |