Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27145253 | 0.90 | MGLL (0.36) | MGLLFAAH | |
| SCHEMBL27139210 | 0.89 | FAAH (0.37) | MGLLFAAH | |
| SCHEMBL27246316 | 0.87 | ENPP2 (0.38) | MGLL | |
| SCHEMBL27246524 | 0.85 | MGLL (0.47) | MGLLALOX5APFEN1FAAH | |
| SCHEMBL27143135 | 0.84 | MGLL (0.45) | MGLLFAAH | |
| SCHEMBL27246248 | 0.79 | MGLL (0.39) | MGLL | |
| SCHEMBL27151411 | 0.78 | NAAA (0.40) | MGLLFAAH | |
| SCHEMBL27246339 | 0.76 | MGLL (0.47) | MGLLFAAH | |
| SCHEMBL25297788 | 0.72 | NAAA (0.36) | MGLLALOX5APFEN1FAAH | |
| SCHEMBL27154641 | 0.71 | MGLL (0.48) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240199587-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240199587-A1 | HETEROCYCLIC COMPOUNDS | CYP1B1, CYP1A1, CYP4B1 | MGLL 4524/4885ALOX5AP 2646/4885FEN1 3253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.