Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.56 |
| ▸ | APAF1 | O14727 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704348 | 0.81 | ACHE (0.67) | ACHESIGMAR1APAF1 | |
| SCHEMBL2186097 | 0.77 | L3MBTL1 (0.70) | ACHESIGMAR1BAZ2B | |
| SCHEMBL16335515 | 0.76 | SIGMAR1 (0.68) | ACHESIGMAR1APAF1 | |
| SCHEMBL9635287 | 0.74 | ACHE (0.60) | ACHESIGMAR1HDAC1HDAC6BAZ2B | |
| Carvotroline SCHEMBL350602 | 0.74 | SIGMAR1 (0.88) | ACHESIGMAR1 | |
| Carvotroline SCHEMBL29710918 | 0.74 | SIGMAR1 (0.88) | ACHESIGMAR1 | |
| Carvotroline SCHEMBL123737 | 0.73 | SIGMAR1 (0.86) | ACHESIGMAR1 | |
| SCHEMBL29171353 | 0.73 | BAZ2B (0.79) | ACHEHDAC1HDAC6BAZ2BAPAF1 | |
| SCHEMBL6215974 | 0.72 | HDAC1 (0.51) | ACHESIGMAR1HDAC1HDAC6BAZ2B | |
| SCHEMBL6215265 | 0.72 | CCR1 (0.55) | ACHEHDAC1HDAC6BAZ2BAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | CULLGEN (SHANGHAI), INC. (CN) | 2024-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240197694-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | DCAF1, DDB1, CUL4A | ACHE 4434/4885SIGMAR1 4137/4885HDAC1 671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.